Evolution of a core gene network for skeletogenesis in chordates.

Evolution of a core gene network for skeletogenesis in chordates.

The skeleton is one of the most important features for the reconstruction of vertebrate phylogeny but few data are available to understand its molecular origin. In mammals the Runt genes are central regulators of skeletogenesis. Runx2 was shown to be essential for osteoblast differentiation, tooth d...

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Bibliographic Details
Main Authors: Jochen Hecht, Sigmar Stricker, Ulrike Wiecha, Asita Stiege, Georgia Panopoulou, Lars Podsiadlowski, Albert J Poustka, Christoph Dieterich, Siegfried Ehrich, Julia Suvorova, Stefan Mundlos, Volkhard Seitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2265531?pdf=render

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http://europepmc.org/articles/PMC2265531?pdf=render

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