Structure-function relationship of cytoplasmic and nuclear IκB proteins: an in silico analysis.
Cytoplasmic IκB proteins are primary regulators that interact with NF-κB subunits in the cytoplasm of unstimulated cells. Upon stimulation, these IκB proteins are rapidly degraded, thus allowing NF-κB to translocate into the nucleus and activate the transcription of genes encoding various immune med...
Main Authors: | Balachandran Manavalan, Shaherin Basith, Yong-Min Choi, Gwang Lee, Sangdun Choi |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-12-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21203422/?tool=EBI |
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