High Levels of Serum DPP-4 Activity Are Associated with Low Bone Mineral Density in Obese Postmenopausal Women

High Levels of Serum DPP-4 Activity Are Associated with Low Bone Mineral Density in Obese Postmenopausal Women

BackgroundDipeptidyl peptidase 4/CD26 (DPP-4) is a widely expressed cell surface serine protease. DPP-4 inhibitors, one of common anti-diabetic agents play a protective role in bone metabolism in recent studies. A soluble form of DPP-4 is found in serum, and exhibits DPP-4 enzymatic activity. Howeve...

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Bibliographic Details
Main Authors: Sang-Wook Kim, Eun-Hee Cho
Format: Article
Language:English
Published: Academya Publishing Co. 2016-03-01
Series:Endocrinology and Metabolism
Subjects:
Dipeptidyl peptidase 4
Bone mineral density
Postmenopause
Women
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-31-93.pdf

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