MglA/SspA complex interactions are modulated by inorganic polyphosphate.

MglA/SspA complex interactions are modulated by inorganic polyphosphate.

The transcription factors MglA and SspA of Francisella tularensis form a heterodimer complex and interact with the RNA polymerase to regulate the expression of the Francisella pathogenicity island (FPI) genes. These genes are essential for this pathogen's virulence and survival within host cell...

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Bibliographic Details
Main Authors: Algevis P Wrench, Christopher L Gardner, Sara D Siegel, Fernando A Pagliai, Mahsa Malekiha, Claudio F Gonzalez, Graciela L Lorca
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3792966?pdf=render

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