Job and environment factors in relation with pleural malignant mesothelioma and determination of occurrence chance of mesothelioma in exposure to asbestos

• Main Authors: S. Mohammad Sadegh, M.M. Heidari, A. Cheraghvandi, SA. Azin, S. Salehpour
• Format: Article
• Language: fas
• Published: Iran University of Medical Sciences 2010-07-01
• Series: Salāmat-i kār-i Īrān
• Subjects: Mesothelioma; asbestos; pleural malignant disease
• Online Access: http://ioh.tums.ac.ir/browse.php?a_code=A-10-1-27&slc_lang=en&sid=1

Background and aimsThe relationship between pleural malignant mesothelioma and exposure to asbestos is well-known, but there is no accurate information regarding high risk occupations and types of exposure in Iran. In this study we specified high risk jobs for asbestos exposure.MethodsIn this case-control study, 64 cases with diagnosis of pleural malignant mesothelioma who were admitted in Masih Daneshvari Hospital between the years 2001 and 2009 were studied. All the cases and 58 controls participated in a telephone interview for job history and occupational and environmental exposures to asbestos.ResultsAsbestos exposed occupations in mesothelioma group included corrugated asbestos cement sheet production 11(%17.2), Insulation 6(%9.4), construction 6(%9.4), asbestos warehouse 3(%4.7), oil and gas shaft drilling 2(%3.1) and car brake shoe manufacturing 2(%3.1). In controls, the only exposed occupation was construction 8(%13.79). Odds Ratio calculated foroccupational exposure to asbestos was 5.51(CI=2.26-13.47). Residency in neighbourhood of corrugated asbestos cement sheet production factory was the most prevalent cause for environmental exposure.ConclusionIn %46.87 of mesothelioma cases, source of exposure to asbestos was corrugated asbestos cement sheet industry due to employment in the factory, residency in neighbourhood of the factory or use of its products.