Aggregation of Human Trophoblast Cells into Three-Dimensional Culture System Enhances Anti-Inflammatory Characteristics through Cytoskeleton Regulation

Aggregation of Human Trophoblast Cells into Three-Dimensional Culture System Enhances Anti-Inflammatory Characteristics through Cytoskeleton Regulation

Background: Three-dimensional (3D) culture changes cell characteristics and function, suggesting that 3D culture provides a more physiologically relevant environment for cells compared with 2D culture. We investigated the differences in cell functions depending on the culture model in human trophobl...

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Bibliographic Details
Main Authors: Kotomi Seno, Yasuhisa Munakata, Michiya Sano, Ryouka Kawahara-Miki, Hironori Takahashi, Akihide Ohkuchi, Hisataka Iwata, Takehito Kuwayama, Koumei Shirasuna
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
inflammation
interleukin-6
regnase-1
trophoblast cells
Online Access:http://www.mdpi.com/1422-0067/19/8/2322

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