BIOCHEMICAL PARAMETERS OF THE INTENSITY OF SYSTEMIC INFLAMMATORY RESPONSE IN THE ASSESSMENT OF BIOCOMPATIBILITY OF POLYCAPROLACTONE/VATERITE SCAFFOLDS

In this study, we analyzed biocompatibility of polycaprolactone/vaterite scaffolds by assessing the dynamics of systemic inflammatory response. We detected an increase in the CRP level after 7 days and no changes in the level TNF-α and IL-1β after 7 and 21 days, which indicates a weak and short-term...

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Main Authors:	E. A. Galashina, Yu. A. Chibrikova, A. N. Ivanov, E. V. Gladkova, I. A. Norkin
Format:	Article
Language:	Russian
Published:	Private institution educational organization of higher education "Medical University "ReaViz" 2020-11-01
Series:	Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Subjects:	scaffolds polycaprolactone vaterite systemic inflammatory response
Online Access:	https://vestnik.reaviz.ru/jour/article/view/31

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spelling	doaj-e5412f54884247b988941cff8e2a99382021-08-17T07:56:40ZrusPrivate institution educational organization of higher education "Medical University "ReaViz"Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье2226-762X2782-15792020-11-01029810328BIOCHEMICAL PARAMETERS OF THE INTENSITY OF SYSTEMIC INFLAMMATORY RESPONSE IN THE ASSESSMENT OF BIOCOMPATIBILITY OF POLYCAPROLACTONE/VATERITE SCAFFOLDSE. A. Galashina0Yu. A. Chibrikova1A. N. Ivanov2E. V. Gladkova3I. A. Norkin4Research Institute of Traumatology, Orthopedics, and Neurosurgery, Federal State Budgetary Institution of Higher Education ‘V.I. Razumovsky Saratov State Medical University,’ Ministry of Health of the Russian FederationFederal State Budgetary Institution of Higher Education ‘V.I. Razumovsky Saratov State Medical University’, Ministry of Health of the Russian FederationResearch Institute of Traumatology, Orthopedics, and Neurosurgery, Federal State Budgetary Institution of Higher Education ‘V.I. Razumovsky Saratov State Medical University,’ Ministry of Health of the Russian FederationResearch Institute of Traumatology, Orthopedics, and Neurosurgery, Federal State Budgetary Institution of Higher Education ‘V.I. Razumovsky Saratov State Medical University,’ Ministry of Health of the Russian FederationResearch Institute of Traumatology, Orthopedics, and Neurosurgery, Federal State Budgetary Institution of Higher Education ‘V.I. Razumovsky Saratov State Medical University,’ Ministry of Health of the Russian FederationIn this study, we analyzed biocompatibility of polycaprolactone/vaterite scaffolds by assessing the dynamics of systemic inflammatory response. We detected an increase in the CRP level after 7 days and no changes in the level TNF-α and IL-1β after 7 and 21 days, which indicates a weak and short-term inflammatory reaction and is a pathogenetic component of matrix biocompatibility.https://vestnik.reaviz.ru/jour/article/view/31scaffoldspolycaprolactonevateritesystemic inflammatory response
collection	DOAJ
language	Russian
format	Article
sources	DOAJ
author	E. A. Galashina Yu. A. Chibrikova A. N. Ivanov E. V. Gladkova I. A. Norkin
spellingShingle	E. A. Galashina Yu. A. Chibrikova A. N. Ivanov E. V. Gladkova I. A. Norkin BIOCHEMICAL PARAMETERS OF THE INTENSITY OF SYSTEMIC INFLAMMATORY RESPONSE IN THE ASSESSMENT OF BIOCOMPATIBILITY OF POLYCAPROLACTONE/VATERITE SCAFFOLDS Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье scaffolds polycaprolactone vaterite systemic inflammatory response
author_facet	E. A. Galashina Yu. A. Chibrikova A. N. Ivanov E. V. Gladkova I. A. Norkin
author_sort	E. A. Galashina
title	BIOCHEMICAL PARAMETERS OF THE INTENSITY OF SYSTEMIC INFLAMMATORY RESPONSE IN THE ASSESSMENT OF BIOCOMPATIBILITY OF POLYCAPROLACTONE/VATERITE SCAFFOLDS
title_short	BIOCHEMICAL PARAMETERS OF THE INTENSITY OF SYSTEMIC INFLAMMATORY RESPONSE IN THE ASSESSMENT OF BIOCOMPATIBILITY OF POLYCAPROLACTONE/VATERITE SCAFFOLDS
title_full	BIOCHEMICAL PARAMETERS OF THE INTENSITY OF SYSTEMIC INFLAMMATORY RESPONSE IN THE ASSESSMENT OF BIOCOMPATIBILITY OF POLYCAPROLACTONE/VATERITE SCAFFOLDS
title_fullStr	BIOCHEMICAL PARAMETERS OF THE INTENSITY OF SYSTEMIC INFLAMMATORY RESPONSE IN THE ASSESSMENT OF BIOCOMPATIBILITY OF POLYCAPROLACTONE/VATERITE SCAFFOLDS
title_full_unstemmed	BIOCHEMICAL PARAMETERS OF THE INTENSITY OF SYSTEMIC INFLAMMATORY RESPONSE IN THE ASSESSMENT OF BIOCOMPATIBILITY OF POLYCAPROLACTONE/VATERITE SCAFFOLDS
title_sort	biochemical parameters of the intensity of systemic inflammatory response in the assessment of biocompatibility of polycaprolactone/vaterite scaffolds
publisher	Private institution educational organization of higher education "Medical University "ReaViz"
series	Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
issn	2226-762X 2782-1579
publishDate	2020-11-01
description	In this study, we analyzed biocompatibility of polycaprolactone/vaterite scaffolds by assessing the dynamics of systemic inflammatory response. We detected an increase in the CRP level after 7 days and no changes in the level TNF-α and IL-1β after 7 and 21 days, which indicates a weak and short-term inflammatory reaction and is a pathogenetic component of matrix biocompatibility.
topic	scaffolds polycaprolactone vaterite systemic inflammatory response
url	https://vestnik.reaviz.ru/jour/article/view/31
work_keys_str_mv	AT eagalashina biochemicalparametersoftheintensityofsystemicinflammatoryresponseintheassessmentofbiocompatibilityofpolycaprolactonevateritescaffolds AT yuachibrikova biochemicalparametersoftheintensityofsystemicinflammatoryresponseintheassessmentofbiocompatibilityofpolycaprolactonevateritescaffolds AT anivanov biochemicalparametersoftheintensityofsystemicinflammatoryresponseintheassessmentofbiocompatibilityofpolycaprolactonevateritescaffolds AT evgladkova biochemicalparametersoftheintensityofsystemicinflammatoryresponseintheassessmentofbiocompatibilityofpolycaprolactonevateritescaffolds AT ianorkin biochemicalparametersoftheintensityofsystemicinflammatoryresponseintheassessmentofbiocompatibilityofpolycaprolactonevateritescaffolds
_version_	1721205387065032704

BIOCHEMICAL PARAMETERS OF THE INTENSITY OF SYSTEMIC INFLAMMATORY RESPONSE IN THE ASSESSMENT OF BIOCOMPATIBILITY OF POLYCAPROLACTONE/VATERITE SCAFFOLDS

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