GAPT regulates cholinergic dysfunction and oxidative stress in the brains of learning and memory impairment mice induced by scopolamine

GAPT regulates cholinergic dysfunction and oxidative stress in the brains of learning and memory impairment mice induced by scopolamine

Abstract Background Cholinergic dysfunction and oxidative stress are the crucial mechanisms of Alzheimer's disease (AD). GAPT, also called GEPT (a combination of several active components extracted from the Chinese herbs ginseng, epimedium, polygala and tuber curcumae) or Jinsiwei, is a patente...

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Bibliographic Details
Main Authors: Zhenhong Liu, Gaofeng Qin, Lulu Mana, Yunfang Dong, Shuaiyang Huang, Yahan Wang, Yiqiong Wu, Jing Shi, Jinzhou Tian, Pengwen Wang
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Brain and Behavior
Subjects:
Alzheimer's disease
behavior
cholinergic system
GAPT
memory impairment
oxidative stress
Online Access:https://doi.org/10.1002/brb3.1602

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