Sex does not clinically influence the functional outcome of total knee arthroplasty but females have a lower rate of satisfaction with pain relief

Abstract Background The aims were to assess whether sex had a clinically significant independent influence on the outcome of total knee arthroplasty (TKA) according to the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, Short Form (SF-) 12 scores and patient satisfactio...

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Main Authors: N. D. Clement, D. Weir, J. Holland, D. J. Deehan
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Knee Surgery & Related Research
Subjects:
Sex
Online Access:https://doi.org/10.1186/s43019-020-00048-1
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spelling doaj-e54c36d9acef41afbfd56cdea3d88b162021-06-20T11:49:52ZengBMCKnee Surgery & Related Research2234-24512020-06-013211710.1186/s43019-020-00048-1Sex does not clinically influence the functional outcome of total knee arthroplasty but females have a lower rate of satisfaction with pain reliefN. D. Clement0D. Weir1J. Holland2D. J. Deehan3Department of Orthopaedics, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation TrustDepartment of Orthopaedics, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation TrustDepartment of Orthopaedics, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation TrustDepartment of Orthopaedics, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation TrustAbstract Background The aims were to assess whether sex had a clinically significant independent influence on the outcome of total knee arthroplasty (TKA) according to the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, Short Form (SF-) 12 scores and patient satisfaction at 1 year. Methods A retrospective cohort of 3510 primary TKA were identified. Patient demographics, comorbidities, WOMAC and SF-12 scores were collected preoperatively and 1 year postoperatively. Patient satisfaction were assessed at 1 year. Results There were 1584 males and 1926 females. The preoperative WOMAC and SF-12 scores were significantly (p < 0.001) worse in females but were not greater than the minimal clinically important difference (MCID). When adjustments had been made for confounding differences, females showed a significantly greater improvement in their function (1.5 points, p = 0.03) and total (1.5 points, p = 0.03) WOMAC scores compared to males, but these were not greater than the MCID. When adjustments had been made for confounding differences, females were less likely to be satisfied with their pain relief (p = 0.03) relative to males. Conclusion Sex does not clinically influence the knee specific outcome (WOMAC) or overall generic (SF-12) health 1 year after TKA. However, satisfaction with pain relief after TKA was significantly less likely in female patients. Level of evidence II Prognostic retrospective cohort study.https://doi.org/10.1186/s43019-020-00048-1SexTotal knee arthroplastyOutcomeSatisfactionWOMAC
collection DOAJ
language English
format Article
sources DOAJ
author N. D. Clement
D. Weir
J. Holland
D. J. Deehan
spellingShingle N. D. Clement
D. Weir
J. Holland
D. J. Deehan
Sex does not clinically influence the functional outcome of total knee arthroplasty but females have a lower rate of satisfaction with pain relief
Knee Surgery & Related Research
Sex
Total knee arthroplasty
Outcome
Satisfaction
WOMAC
author_facet N. D. Clement
D. Weir
J. Holland
D. J. Deehan
author_sort N. D. Clement
title Sex does not clinically influence the functional outcome of total knee arthroplasty but females have a lower rate of satisfaction with pain relief
title_short Sex does not clinically influence the functional outcome of total knee arthroplasty but females have a lower rate of satisfaction with pain relief
title_full Sex does not clinically influence the functional outcome of total knee arthroplasty but females have a lower rate of satisfaction with pain relief
title_fullStr Sex does not clinically influence the functional outcome of total knee arthroplasty but females have a lower rate of satisfaction with pain relief
title_full_unstemmed Sex does not clinically influence the functional outcome of total knee arthroplasty but females have a lower rate of satisfaction with pain relief
title_sort sex does not clinically influence the functional outcome of total knee arthroplasty but females have a lower rate of satisfaction with pain relief
publisher BMC
series Knee Surgery & Related Research
issn 2234-2451
publishDate 2020-06-01
description Abstract Background The aims were to assess whether sex had a clinically significant independent influence on the outcome of total knee arthroplasty (TKA) according to the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, Short Form (SF-) 12 scores and patient satisfaction at 1 year. Methods A retrospective cohort of 3510 primary TKA were identified. Patient demographics, comorbidities, WOMAC and SF-12 scores were collected preoperatively and 1 year postoperatively. Patient satisfaction were assessed at 1 year. Results There were 1584 males and 1926 females. The preoperative WOMAC and SF-12 scores were significantly (p < 0.001) worse in females but were not greater than the minimal clinically important difference (MCID). When adjustments had been made for confounding differences, females showed a significantly greater improvement in their function (1.5 points, p = 0.03) and total (1.5 points, p = 0.03) WOMAC scores compared to males, but these were not greater than the MCID. When adjustments had been made for confounding differences, females were less likely to be satisfied with their pain relief (p = 0.03) relative to males. Conclusion Sex does not clinically influence the knee specific outcome (WOMAC) or overall generic (SF-12) health 1 year after TKA. However, satisfaction with pain relief after TKA was significantly less likely in female patients. Level of evidence II Prognostic retrospective cohort study.
topic Sex
Total knee arthroplasty
Outcome
Satisfaction
WOMAC
url https://doi.org/10.1186/s43019-020-00048-1
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