Achievement of sustained deep remission with adalimumab in a patient with both refractory ulcerative colitis and seronegative erosive rheumatoid arthritis

Inflammatory bowel disease (IBD) is commonly associated with peripheral inflammatory arthritis, and it has been estimated that as many as 12% of IBD patients report these manifestations. However, rheumatoid arthritis (RA) is rarely associated with ulcerative colitis (UC). Among all the biological ag...

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Main Authors: G. Andrisani, E. Gremese, L. Guidi, A. Papa, M. Marzo, C. Felice, D. Pugliese, A. Armuzzi
Format: Article
Language:English
Published: PAGEPress Publications 2013-05-01
Series:Reumatismo
Subjects:
Online Access:http://www.reumatismo.org/index.php/reuma/article/view/648
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spelling doaj-e55118c5592a46779678e93b1ec3dfc12020-11-24T23:27:09ZengPAGEPress PublicationsReumatismo0048-74492240-26832013-05-01652757810.4081/reumatismo.2013.75598Achievement of sustained deep remission with adalimumab in a patient with both refractory ulcerative colitis and seronegative erosive rheumatoid arthritisG. Andrisani0E. Gremese1L. Guidi2A. Papa3M. Marzo4C. Felice5D. Pugliese6A. Armuzzi7Internal Medicine and Gastroenterology Unit, Complesso Integrato Columbus, Catholic University, RomeRheumatology Unit, Complesso Integrato Columbus, Catholic University, RomeInternal Medicine and Gastroenterology Unit, Complesso Integrato Columbus, Catholic University, RomeInternal Medicine and Gastroenterology Unit, Complesso Integrato Columbus, Catholic University, RomeInternal Medicine and Gastroenterology Unit, Complesso Integrato Columbus, Catholic University, RomeInternal Medicine and Gastroenterology Unit, Complesso Integrato Columbus, Catholic University, RomeInternal Medicine and Gastroenterology Unit, Complesso Integrato Columbus, Catholic University, RomeInternal Medicine and Gastroenterology Unit, Complesso Integrato Columbus, Catholic University, RomeInflammatory bowel disease (IBD) is commonly associated with peripheral inflammatory arthritis, and it has been estimated that as many as 12% of IBD patients report these manifestations. However, rheumatoid arthritis (RA) is rarely associated with ulcerative colitis (UC). Among all the biological agents available, nine have been currently approved for the treatment of RA. Conversely, only Infliximab and recently Adalimumab have been approved for UC. In particular, the efficacy of Adalimumab in UC has been demonstrated by both recent randomized controlled trials and real-life studies. Moreover, Adalimumab is a well-established treatment for RA. Herein, we describe a patient with RA and UC treated successfully with ADA.http://www.reumatismo.org/index.php/reuma/article/view/648Ulcerative colitis, Rheumatoid arthritis, Adalimumab.
collection DOAJ
language English
format Article
sources DOAJ
author G. Andrisani
E. Gremese
L. Guidi
A. Papa
M. Marzo
C. Felice
D. Pugliese
A. Armuzzi
spellingShingle G. Andrisani
E. Gremese
L. Guidi
A. Papa
M. Marzo
C. Felice
D. Pugliese
A. Armuzzi
Achievement of sustained deep remission with adalimumab in a patient with both refractory ulcerative colitis and seronegative erosive rheumatoid arthritis
Reumatismo
Ulcerative colitis, Rheumatoid arthritis, Adalimumab.
author_facet G. Andrisani
E. Gremese
L. Guidi
A. Papa
M. Marzo
C. Felice
D. Pugliese
A. Armuzzi
author_sort G. Andrisani
title Achievement of sustained deep remission with adalimumab in a patient with both refractory ulcerative colitis and seronegative erosive rheumatoid arthritis
title_short Achievement of sustained deep remission with adalimumab in a patient with both refractory ulcerative colitis and seronegative erosive rheumatoid arthritis
title_full Achievement of sustained deep remission with adalimumab in a patient with both refractory ulcerative colitis and seronegative erosive rheumatoid arthritis
title_fullStr Achievement of sustained deep remission with adalimumab in a patient with both refractory ulcerative colitis and seronegative erosive rheumatoid arthritis
title_full_unstemmed Achievement of sustained deep remission with adalimumab in a patient with both refractory ulcerative colitis and seronegative erosive rheumatoid arthritis
title_sort achievement of sustained deep remission with adalimumab in a patient with both refractory ulcerative colitis and seronegative erosive rheumatoid arthritis
publisher PAGEPress Publications
series Reumatismo
issn 0048-7449
2240-2683
publishDate 2013-05-01
description Inflammatory bowel disease (IBD) is commonly associated with peripheral inflammatory arthritis, and it has been estimated that as many as 12% of IBD patients report these manifestations. However, rheumatoid arthritis (RA) is rarely associated with ulcerative colitis (UC). Among all the biological agents available, nine have been currently approved for the treatment of RA. Conversely, only Infliximab and recently Adalimumab have been approved for UC. In particular, the efficacy of Adalimumab in UC has been demonstrated by both recent randomized controlled trials and real-life studies. Moreover, Adalimumab is a well-established treatment for RA. Herein, we describe a patient with RA and UC treated successfully with ADA.
topic Ulcerative colitis, Rheumatoid arthritis, Adalimumab.
url http://www.reumatismo.org/index.php/reuma/article/view/648
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