Rotational Mechanism Model of the Bacterial V1 Motor Based on Structural and Computational Analyses

Rotational Mechanism Model of the Bacterial V1 Motor Based on Structural and Computational Analyses

V1-ATPase exemplifies the ubiquitous rotary motor, in which a central shaft DF complex rotates inside a hexagonally arranged catalytic A3B3 complex, powered by the energy from ATP hydrolysis. We have recently reported a number of crystal structures of the Enterococcus hirae A3B3DF (V1) complex corre...

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Bibliographic Details
Main Authors: Abhishek Singharoy, Chris Chipot, Toru Ekimoto, Kano Suzuki, Mitsunori Ikeguchi, Ichiro Yamato, Takeshi Murata
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Physiology
Subjects:
rotary motor
V-ATPase
X-ray structure
molecular dynamics
free energy
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00046/full

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