Glutamate and GABA transporters in brain

Glutamate and GABA transporters in brain

The mammalian genome contains four genes encoding GABA transporters (GAT1, slc6a1; GAT2, slc6a13; GAT3, slc6a11; BGT1, slc6a12) and five glutamate transporter genes (EAAT1, slc1a3; EAAT2, slc1a2; EAAT3, slc1a1; EAAT4, slc1a6; EAAT5, slc1a7). These transporters keep the extracellular levels of GABA a...

Full description

Bibliographic Details
Main Authors:	Yun eZhou, Niels Christian Danbolt
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2013-11-01
Series:	Frontiers in Endocrinology
Subjects:	EAAT2 Glutamate Uptake GABA uptake BGT1 GAT1 GAT3
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00165/full

Similar Items

Structure, function and plasticity of GABA transporters
by: Annalisa eScimemi
Published: (2014-06-01)

PLASMA MEMBRANE TRANSPORTERS GAT-1 AND GAT-3 CONTRIBUTE TO HETEROGENEITY OF GABAERGIC SYNAPSES IN NEOCORTEX
by: Marcello eMelone, et al.
Published: (2014-07-01)

The Transporter GAT1 Plays an Important Role in GABA-mediated Carbon-Nitrogen Interactions in Arabidopsis
by: Albert eBatushansky, et al.
Published: (2015-09-01)

Rapid compensatory changes in the expression of EAAT-3 and GAT-1 transporters during seizures in cells of the CA1 and dentate gyrus
by: Medina-Ceja Laura, et al.
Published: (2012-08-01)

A role for GAT-1 in Presynaptic GABA Homeostasis?
by: Fiorenzo eConti, et al.
Published: (2011-04-01)

Preventative and therapeutic effects of a GABA transporter 1 inhibitor administered systemically in a mouse model of paclitaxel-induced neuropathic pain
by: Willias Masocha, et al.
Published: (2016-12-01)

GRID-independent molecular descriptor analysis and molecular docking studies to mimic the binding hypothesis of γ-aminobutyric acid transporter 1 (GAT1) inhibitors
by: Sadia Zafar, et al.
Published: (2019-01-01)

Expression of functional inhibitory neurotransmitter transporters GlyT1, GAT-1, and GAT-3 by astrocytes of inferior colliculus and hippocampus
by: Elsa Ghirardini, et al.
Published: (2018-01-01)

Expression, purification and structural analysis of functional GABA transporter 1 using the baculovirus expression system
by: Jing Hu, et al.
Published: (2017-05-01)

Regulation of Glutamate, GABA and Dopamine Transporter Uptake, Surface Mobility and Expression
by: Renae M. Ryan, et al.
Published: (2021-04-01)

Astrocytic GABA transporter controls sleep by modulating GABAergic signaling in Drosophila circadian neurons
by: Chaturvedi, R., et al.
Published: (2022)

The Regulation of Astrocytic Glutamate Transporters in Health and Neurodegenerative Diseases
by: Alison C. Todd, et al.
Published: (2020-12-01)

A Reappraisal of GAT-1 Localization in Neocortex
by: Giorgia Fattorini, et al.
Published: (2020-02-01)

Midbrain dopamine neurons sustain inhibitory transmission using plasma membrane uptake of GABA, not synthesis
by: Nicolas X Tritsch, et al.
Published: (2014-04-01)

Molecular Dynamic Simulations to Probe Stereoselectivity of Tiagabine Binding with Human GAT1
by: Sadia Zafar, et al.
Published: (2020-10-01)

Inhibitors of glutamate dehydrogenase block sodium-dependent glutamate uptake in rat brain membranes
by: Brendan S Whitelaw, et al.
Published: (2013-09-01)

Targeting glutamate uptake to treat alcohol use disorders
by: P.S.S. eRao, et al.
Published: (2015-04-01)

Role of glutamate transporter 1 in the attenuation of alcohol intake
by: Youssef eSari
Published: (2014-07-01)

Effets du cuivre (II) sur le transport à haute affinité du glutamate dans des astrocytes en culture : proposition d'un mécanisme physiopathologique de la maladie de Wilson
by: Pannunzio, Marc
Published: (2016)

The legacy of József Gát on piano performance and pedagogy
by: Bascom, Brandon Roger
Published: (2012)

Glutamate Transport and Preterm Brain Injury
by: Silvia Pregnolato, et al.
Published: (2019-04-01)

Towards a Better Understanding of GABAergic Remodeling in Alzheimer’s Disease
by: Karan Govindpani, et al.
Published: (2017-08-01)

Molecular Determinants and Pharmacological Analysis for a Class of Competitive Non-transported Bicyclic Inhibitors of the Betaine/GABA Transporter BGT1
by: Stefanie Kickinger, et al.
Published: (2021-09-01)

GATS服務委外相關問題之研究
by: 賴一帆

Selective up-regulation of the glial Na+-dependent glutamate transporter GLT1 by a neuroimmunophilin ligand results in neuroprotection
by: Raquelli Ganel, et al.
Published: (2006-03-01)

Changes in glial glutamate transporters in human epileptogenic hippocampus: Inadequate explanation for high extracellular glutamate during seizures
by: L.P. Bjørnsen, et al.
Published: (2007-02-01)

Structure, Function, and Modulation of γ-Aminobutyric Acid Transporter 1 (GAT1) in Neurological Disorders: A Pharmacoinformatic Prospective
by: Sadia Zafar, et al.
Published: (2018-09-01)

Neurochemical and behavioral characterization of neuronal glutamate transporter EAAT3 heterozygous mice
by: Luis F. González, et al.
Published: (2017-09-01)

Glutamate signalling in bone.
by: Karen eBrakspear, et al.
Published: (2012-08-01)

The amino acid transporters of the glutamate/GABA-glutamine cycle and their impact on insulin and glucagon secretion
by: Monica eJenstad, et al.
Published: (2013-12-01)

NLRX1 Enhances Glutamate Uptake and Inhibits Glutamate Release by Astrocytes
by: Shaimaa Mahmoud, et al.
Published: (2019-04-01)

Estrogen and progesterone attenuate glutamate neurotoxicity via regulation of EAAT3 and GLT-1 in a rat model of ischemic stroke
by: Sara Nemati Pour, et al.
Published: (2020-10-01)

Plasticity of GABA transporters: an unconventional route to shape inhibitory synaptic transmission
by: Annalisa eScimemi
Published: (2014-05-01)

Cigarette smoking among economically active population
by: Dorota Kaleta, et al.
Published: (2013-06-01)

Afinal, o que a organização mundial do comércio tem a ver com a educação superior? Please enlighten me: what does the world trade organization have to do with higher education?
by: Gustavo Ferreira Ribeiro
Published: (2006-12-01)

Role of glutamate transporter EAAT2 in survival of silk worm Bombyx mori at higher dosages of Azaserine, an analogue of glutamine
by: M D Venkatesh, et al.
Published: (2018-07-01)

Disruption of Glutamate Transport and Homeostasis by Acute Metabolic Stress
by: Stefan Passlick, et al.
Published: (2021-02-01)

GABA and glutamate in schizophrenia: A 7 T 1H-MRS study
by: Anouk Marsman, et al.
Published: (2014-01-01)

Low Micromolar Ba2+ Potentiates Glutamate Transporter Current in Hippocampal Astrocytes
by: Ramil eAfzalov, et al.
Published: (2013-08-01)

Jian-Pi-Zhi-Dong-Decoction regulates the expression of glutamate transporters to attenuate glutamate excitotoxicity and exerts anti-tics effects in Tourette syndrome model rats
by: Yu W, et al.
Published: (2018-12-01)