A distal centriolar protein network controls organelle maturation and asymmetry

A distal centriolar protein network controls organelle maturation and asymmetry

Removal of daughter centriole-specific/enriched proteins (DCPs) and assembly of distal appendages (DA) are important for centrosome asymmetry. Here, the authors report that a centriolar distal end protein network regulates DCP removal, DA assembly, and ciliary vesicle docking.

Bibliographic Details
Main Authors: Lei Wang, Marion Failler, Wenxiang Fu, Brian D. Dynlacht
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06286-y
id doaj-e5a44ed5c8f24e55aa9895b427dfc9f0
record_format Article
spelling doaj-e5a44ed5c8f24e55aa9895b427dfc9f02021-05-11T10:22:08ZengNature Publishing GroupNature Communications2041-17232018-09-019111510.1038/s41467-018-06286-yA distal centriolar protein network controls organelle maturation and asymmetryLei Wang0Marion Failler1Wenxiang Fu2Brian D. Dynlacht3Department of Pathology, New York University Cancer Institute, New York University School of MedicineDepartment of Pathology, New York University Cancer Institute, New York University School of MedicineDepartment of Pathology, New York University Cancer Institute, New York University School of MedicineDepartment of Pathology, New York University Cancer Institute, New York University School of MedicineRemoval of daughter centriole-specific/enriched proteins (DCPs) and assembly of distal appendages (DA) are important for centrosome asymmetry. Here, the authors report that a centriolar distal end protein network regulates DCP removal, DA assembly, and ciliary vesicle docking.https://doi.org/10.1038/s41467-018-06286-y
collection DOAJ
language English
format Article
sources DOAJ
author Lei Wang
Marion Failler
Wenxiang Fu
Brian D. Dynlacht
spellingShingle Lei Wang
Marion Failler
Wenxiang Fu
Brian D. Dynlacht
A distal centriolar protein network controls organelle maturation and asymmetry
Nature Communications
author_facet Lei Wang
Marion Failler
Wenxiang Fu
Brian D. Dynlacht
author_sort Lei Wang
title A distal centriolar protein network controls organelle maturation and asymmetry
title_short A distal centriolar protein network controls organelle maturation and asymmetry
title_full A distal centriolar protein network controls organelle maturation and asymmetry
title_fullStr A distal centriolar protein network controls organelle maturation and asymmetry
title_full_unstemmed A distal centriolar protein network controls organelle maturation and asymmetry
title_sort distal centriolar protein network controls organelle maturation and asymmetry
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2018-09-01
description Removal of daughter centriole-specific/enriched proteins (DCPs) and assembly of distal appendages (DA) are important for centrosome asymmetry. Here, the authors report that a centriolar distal end protein network regulates DCP removal, DA assembly, and ciliary vesicle docking.
url https://doi.org/10.1038/s41467-018-06286-y
work_keys_str_mv AT leiwang adistalcentriolarproteinnetworkcontrolsorganellematurationandasymmetry
AT marionfailler adistalcentriolarproteinnetworkcontrolsorganellematurationandasymmetry
AT wenxiangfu adistalcentriolarproteinnetworkcontrolsorganellematurationandasymmetry
AT brianddynlacht adistalcentriolarproteinnetworkcontrolsorganellematurationandasymmetry
AT leiwang distalcentriolarproteinnetworkcontrolsorganellematurationandasymmetry
AT marionfailler distalcentriolarproteinnetworkcontrolsorganellematurationandasymmetry
AT wenxiangfu distalcentriolarproteinnetworkcontrolsorganellematurationandasymmetry
AT brianddynlacht distalcentriolarproteinnetworkcontrolsorganellematurationandasymmetry
_version_ 1721448334498988032

Similar Items