Chondroitinase ABC Treatment Enhances Synaptogenesis between Transplant and Host Neurons in Model of Retinal Degeneration

Although recent studies revealed chondroitinase ABC (ChABC), an enzyme that degrades chondroitin sulfate proteoglycans, promotes CNS regeneration in vivo, the usefulness of its application for transplantation is not clear. We investigated if treatment with ChABC can promote synapse formation between...

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Bibliographic Details
Main Authors: Takuya Suzuki, Masayuki Akimoto, Hiroo Imai, Yoshiki Ueda, Michiko Mandai, Nagahisa Yoshimura, Anand Swaroop, Masayo Takahashi
Format: Article
Language:English
Published: SAGE Publishing 2007-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000007783464966