Rab 25: Oncogenes and Tumor Suppressive of Cancer

Rab 25: Oncogenes and Tumor Suppressive of Cancer

Rab 25 is a small GTPase belonging to the RAS (rat sarcoma) superfamily. It is expressed in epithelial cells only and serves as a regulator of various intracellular signaling pathways. As a key player in in cell regulation, Rab 25 has been shown by research to function mainly as an oncogene in vario...

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Main Author: Chen Flora
Format: Article
Language:English
Published: EDP Sciences 2021-01-01
Series:E3S Web of Conferences
Online Access:https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/21/e3sconf_aeecs2021_03050.pdf
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spelling doaj-e60121ab5439415fb829b907e05834342021-05-04T12:17:12ZengEDP SciencesE3S Web of Conferences2267-12422021-01-012450305010.1051/e3sconf/202124503050e3sconf_aeecs2021_03050Rab 25: Oncogenes and Tumor Suppressive of CancerChen Flora0University of CaliforniaRab 25 is a small GTPase belonging to the RAS (rat sarcoma) superfamily. It is expressed in epithelial cells only and serves as a regulator of various intracellular signaling pathways. As a key player in in cell regulation, Rab 25 has been shown by research to function mainly as an oncogene in various cancers including breast cancer and ovarian cancer. However, Rab 25 has also been reported to be a tumor suppressor in cancer types such as colorectal cancer. A lot of research has been done about Rab 25 in recent years. This review is an overview of Rab 25, focusing on their role in human diseases such as cancer.https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/21/e3sconf_aeecs2021_03050.pdf
collection DOAJ
language English
format Article
sources DOAJ
author Chen Flora
spellingShingle Chen Flora
Rab 25: Oncogenes and Tumor Suppressive of Cancer
E3S Web of Conferences
author_facet Chen Flora
author_sort Chen Flora
title Rab 25: Oncogenes and Tumor Suppressive of Cancer
title_short Rab 25: Oncogenes and Tumor Suppressive of Cancer
title_full Rab 25: Oncogenes and Tumor Suppressive of Cancer
title_fullStr Rab 25: Oncogenes and Tumor Suppressive of Cancer
title_full_unstemmed Rab 25: Oncogenes and Tumor Suppressive of Cancer
title_sort rab 25: oncogenes and tumor suppressive of cancer
publisher EDP Sciences
series E3S Web of Conferences
issn 2267-1242
publishDate 2021-01-01
description Rab 25 is a small GTPase belonging to the RAS (rat sarcoma) superfamily. It is expressed in epithelial cells only and serves as a regulator of various intracellular signaling pathways. As a key player in in cell regulation, Rab 25 has been shown by research to function mainly as an oncogene in various cancers including breast cancer and ovarian cancer. However, Rab 25 has also been reported to be a tumor suppressor in cancer types such as colorectal cancer. A lot of research has been done about Rab 25 in recent years. This review is an overview of Rab 25, focusing on their role in human diseases such as cancer.
url https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/21/e3sconf_aeecs2021_03050.pdf
work_keys_str_mv AT chenflora rab25oncogenesandtumorsuppressiveofcancer
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