Cytokine network in scrub typhus: high levels of interleukin-8 are associated with disease severity and mortality.

BACKGROUND: Scrub typhus, caused by Orientia tsutsugamushi, is endemic in the Asia-Pacific region. Mortality is high if untreated, and even with treatment as high as 10-20%, further knowledge of the immune response during scrub typhus is needed. The current study was aimed at comparing plasma levels...

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Bibliographic Details
Main Authors: Elisabeth Astrup, Jeshina Janardhanan, Kari Otterdal, Thor Ueland, John A J Prakash, Tove Lekva, Øystein A Strand, O C Abraham, Kurien Thomas, Jan Kristian Damås, Prasad Mathews, Dilip Mathai, Pål Aukrust, George M Varghese
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3916254?pdf=render

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