Cytokine network in scrub typhus: high levels of interleukin-8 are associated with disease severity and mortality.
BACKGROUND: Scrub typhus, caused by Orientia tsutsugamushi, is endemic in the Asia-Pacific region. Mortality is high if untreated, and even with treatment as high as 10-20%, further knowledge of the immune response during scrub typhus is needed. The current study was aimed at comparing plasma levels...
Main Authors: | Elisabeth Astrup, Jeshina Janardhanan, Kari Otterdal, Thor Ueland, John A J Prakash, Tove Lekva, Øystein A Strand, O C Abraham, Kurien Thomas, Jan Kristian Damås, Prasad Mathews, Dilip Mathai, Pål Aukrust, George M Varghese |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-02-01
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Series: | PLoS Neglected Tropical Diseases |
Online Access: | http://europepmc.org/articles/PMC3916254?pdf=render |
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