Glycyrrhizic Acid Prevents Diabetic Nephropathy by Activating AMPK/SIRT1/PGC-1α Signaling in db/db Mice

Glycyrrhizic Acid Prevents Diabetic Nephropathy by Activating AMPK/SIRT1/PGC-1α Signaling in db/db Mice

Diabetic nephropathy (DN) is a major cause of end-stage renal disease (ESRD). Glycyrrhizic acid (GA) is an effective inhibitor of reactive oxygen species (ROS) production. We investigated the role of GA in the progression of renal injury in DN. Albumin (Alb)/creatinine (crea) levels were significant...

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Bibliographic Details
Main Authors:	Shaozhang Hou, Ting Zhang, Yuan Li, Fengying Guo, Xiu Jin
Format:	Article
Language:	English
Published:	Hindawi Limited 2017-01-01
Series:	Journal of Diabetes Research
Online Access:	http://dx.doi.org/10.1155/2017/2865912

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