GDF15 and Growth Control

GDF15 and Growth Control

Growth/differentiation factor-15 (GDF-15) is a distant member of the transforming growth factor β (TGF-β) superfamily and is widely expressed in multiple mammalian tissues. Its expression is highly regulated and is often induced in response to conditions associated with cellular stress. GDF15 serum...

Full description

Bibliographic Details
Main Authors:	Paul J. Emmerson, Kevin L. Duffin, Sudhakar Chintharlapalli, Xinle Wu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-11-01
Series:	Frontiers in Physiology
Subjects:	GDF15 TGFβ GFRAL obesity metabolic cancer
Online Access:	https://www.frontiersin.org/article/10.3389/fphys.2018.01712/full

Similar Items

GDF-15 as a Weight Watcher for Diabetic and Non-Diabetic People Treated With Metformin
by: Jing Ouyang, et al.
Published: (2020-11-01)

The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling
by: Amy A Worth, et al.
Published: (2020-07-01)

Targeting both sides of the GDF15-GFRAL-RET receptor complex: A new approach to achieve body weight homeostasis
by: Fei Li, et al.
Published: (2017-12-01)

Role of GDF15 in radiosensitivity of breast cancer cells
by: Schilling-Tóth Boglárka, et al.
Published: (2014-10-01)

Supraphysiologic Administration of GDF11 Induces Cachexia in Part by Upregulating GDF15
by: Juli E. Jones, et al.
Published: (2018-02-01)

Further evidence of accelerated aging in bipolar disorder: Focus on GDF-15
by: Yang Fang, et al.
Published: (2018-03-01)

GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK
by: David Aguilar-Recarte, et al.
Published: (2021-08-01)

Growth Differentiation Factor-15 (GDF-15) Is Associated With Mortality in Ischemic Stroke Patients Treated With Acute Revascularization Therapy
by: Céline Brenière, et al.
Published: (2019-06-01)

Longitudinal Growth Differentiation Factor 15 (GDF15) and Long-term Intraocular Pressure Fluctuation in Glaucoma: A Pilot Study
by: Jonathan B. Lin, et al.
Published: (2021-01-01)

SCAP Mediated GDF15-Induced Invasion and EMT of Esophageal Cancer
by: Gang Dong, et al.
Published: (2020-10-01)

GDF15 and Cardiac Cells: Current Concepts and New Insights
by: Luc Rochette, et al.
Published: (2021-08-01)

Stellenwert von GDF-15 bei Patienten mit einer diastolischen Dysfunktion und Herzinsuffizienz mit erhaltener linksventrikulärer Ejektionsfraktion
by: Gabriel, Fabian
Published: (2014)

Association between Growth Differentiation Factor-15 (GDF-15) Serum Levels, Anorexia and Low Muscle Mass among Cancer Patients
by: Alessio Molfino, et al.
Published: (2021-12-01)

The Role of Growth Differentiation Factor 15 in Energy Metabolism
by: Joon Young Chang, et al.
Published: (2020-06-01)

Growth/Differentiation Factor-15 (GDF-15): From Biomarker to Novel Targetable Immune Checkpoint
by: Jörg Wischhusen, et al.
Published: (2020-05-01)

Circulating levels of GDF15 in patients with myalgic encephalomyelitis/chronic fatigue syndrome
by: A. Melvin, et al.
Published: (2019-12-01)

Growth differentiation factor 15 as a potential therapeutic for treating obesity
by: Clarence Hale, et al.
Published: (2021-04-01)

Saturated Fatty Acids Promote GDF15 Expression in Human Macrophages through the PERK/eIF2/CHOP Signaling Pathway
by: Laurent L’homme, et al.
Published: (2020-12-01)

GDF15 in the Physiological Human Pregnancy: Novel Data and A Systematic Review
by: Aleksandrova AA, et al.
Published: (2015-10-01)

The Mitochondrial Biomarkers FGF-21 and GDF-15 in Patients with Episodic and Chronic Migraine
by: Philipp Burow, et al.
Published: (2021-09-01)

GDF15 promotes the proliferation of cervical cancer cells by phosphorylating AKT1 and Erk1/2 through the receptor ErbB2
by: Shan Li, et al.
Published: (2018-04-01)

Treatment of Exogenous GDF9 and BMP15 during In vitro Maturation of Oocytes increases the Cell Number of Blastocysts in Pigs
by: Min Ju Kim, et al.
Published: (2016-03-01)

Expression of Hepcidin and Growth Differentiation Factor 15 (GDF-15) Levels in Thalassemia Patients with Iron Overload and Positive Anti Hepatitis C Virus
by: Nuri Dyah Indrasari, et al.
Published: (2016-09-01)

Molecular mechanisms of growth differentiation factor 8 (GDF8) latency, activation, and antagonism.
by: McCoy, Jason
Published: (2020)

The clinical potential of GDF15 as a “ready-to-feed indicator” for critically ill adults
by: Lisa Van Dyck, et al.
Published: (2020-09-01)

Serum GDF-15 level in rheumatoid arthritis: relationship with disease activity and subclinical atherosclerosis
by: Osman Tanrıkulu, et al.
Published: (2017-01-01)

Increased Growth Differentiation Factor 15 in Patients with Hypoleptinemia-Associated Lipodystrophy
by: Susan Kralisch, et al.
Published: (2020-09-01)

Growth and differentiation factor 15 regulates PD-L1 expression in glioblastoma
by: Peng H, et al.
Published: (2019-04-01)

A Novel Role of Growth Differentiation Factor (GDF)-15 in Overlap with Sedentary Lifestyle and Cognitive Risk in COPD
by: Tsunahiko Hirano, et al.
Published: (2020-08-01)

Heightened levels of plasma growth differentiation factor 15 in men living with HIV
by: Agarwal, N., et al.
Published: (2022)

Altered GDF15 and FGF21 Levels in Response to Strenuous Exercise: A Study in Marathon Runners
by: Laura Campderrós, et al.
Published: (2020-11-01)

GDF11 Implications in Cancer Biology and Metabolism. Facts and Controversies
by: Arturo Simoni-Nieves, et al.
Published: (2019-10-01)

Circulating FGF21 and GDF15 as Biomarkers for Screening, Diagnosis, and Severity Assessment of Primary Mitochondrial Disorders in Children
by: Chen, M., et al.
Published: (2022)

Plasma Gelsolin Reinforces the Diagnostic Value of FGF-21 and GDF-15 for Mitochondrial Disorders
by: Ana Peñas, et al.
Published: (2021-06-01)

Quercetin Induces Anticancer Activity by Upregulating Pro-NAG-1/GDF15 in Differentiated Thyroid Cancer Cells
by: Yukyung Hong, et al.
Published: (2021-06-01)

GDF15 Plasma Level Is Inversely Associated With Level of Physical Activity and Correlates With Markers of Inflammation and Muscle Weakness
by: Maria Conte, et al.
Published: (2020-05-01)

The Clinical Value of GDF15 and Its Prospective Mechanism in Sepsis
by: Huan Li, et al.
Published: (2021-09-01)

Proteinase-Activated Receptor 2 Is a Novel Regulator of TGF-β Signaling in Pancreatic Cancer
by: David Witte, et al.
Published: (2016-11-01)

The Role of the TGF-β Superfamily in Myocardial Infarction
by: Anis Hanna, et al.
Published: (2019-09-01)

Pericardial NT-Pro-BNP and GDF-15 as Biomarkers of Atrial Fibrillation and Atrial Matrix Remodeling in Aortic Stenosis
by: Mariana Fragão-Marques, et al.
Published: (2021-08-01)