Selector genes display tumor cooperation and inhibition in Drosophila epithelium in a developmental context-dependent manner
During animal development, selector genes determine identities of body segments and those of individual organs. Selector genes are also misexpressed in cancers, although their contributions to tumor progression per se remain poorly understood. Using a model of cooperative tumorigenesis, we show that...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2017-11-01
|
Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/6/11/1581 |