Hospital effluents as a reservoir of beta-lactamase- and carbapenemase-producing Enterobacteriaceae
The aim of this study was to determine the presence of beta-lactamase- (bla) producing Enterobacteriaceae in hospital effluent samples from two level II and III hospitals in Lima, Peru. The resistance profile of the isolated bacteria was identified and characterized using the MicroScan system for 18...
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Instituto Nacional de Salud
2021-08-01
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Series: | Revista Peruana de Medicina Experimental y Salud Pública |
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Online Access: | https://rpmesp.ins.gob.pe/rpmesp/article/view/6202 |
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doaj-e6622c9d266a4e9c945077e21624fa4b2021-09-03T17:31:09ZspaInstituto Nacional de SaludRevista Peruana de Medicina Experimental y Salud Pública1726-46341726-46422021-08-01382302710.17843/rpmesp.2021.382.62022502Hospital effluents as a reservoir of beta-lactamase- and carbapenemase-producing EnterobacteriaceaeDavid R. Soriano-Moreno0José Yareta1Ana F. Rojas-Cosi2Alexander Fajardo-Loyola3Diana León-Luna4Isabel Castillo-Quezada5Mario Laura-Bejarano6Milagros Hilario-Sánchez7Marco Galarza-Pérez8Pool Marcos-Carbajal9UNIVERSIDAD PERUANA UNIÓNUNIVERSIDAD PERUANA UNIÓNUNIVERSIDAD PERUANA UNIÓNUNIVERSIDAD PERUANA UNIÓNUNIVERSIDAD PERUANA UNIÓNUNIVERSIDAD PERUANA UNIÓNUNIVERSIDAD PERUANA UNIÓNUNIVERSIDAD PERUANA UNIÓNUNIVERSIDAD PERUANA UNIÓNUNIVERSIDAD PERUANA UNIÓNThe aim of this study was to determine the presence of beta-lactamase- (bla) producing Enterobacteriaceae in hospital effluent samples from two level II and III hospitals in Lima, Peru. The resistance profile of the isolated bacteria was identified and characterized using the MicroScan system for 18 antimicrobials, and the presence of extended spectrum beta-lactamases (ESBL) (blaCTX-M, blaSHV blaTEM, blaPER) and carbapenemases (blaKPC, blaNDM, blaVIM, blaIMP) resistance genes was determined by conventional PCR. Thirty-two isolates were identified (20 Enterobacteriaceae and 12 gram-negative bacteria). All the isolated bacteria showed multidrug resistance. ESBL (blaTEM) and carbapenemase (blaKPC, blaIMP) genes were found in samples from the hospitals that we evaluated. The release of these microorganisms to public areas and the lack of treatment of the hospital effluents could be an important public health problem.https://rpmesp.ins.gob.pe/rpmesp/article/view/6202resistencia bacterianafarmacorresistencia bacteriana múltipleantimicrobianosaguas residualesalcantarilladosalud públicahospitales públicosperú |
collection |
DOAJ |
language |
Spanish |
format |
Article |
sources |
DOAJ |
author |
David R. Soriano-Moreno José Yareta Ana F. Rojas-Cosi Alexander Fajardo-Loyola Diana León-Luna Isabel Castillo-Quezada Mario Laura-Bejarano Milagros Hilario-Sánchez Marco Galarza-Pérez Pool Marcos-Carbajal |
spellingShingle |
David R. Soriano-Moreno José Yareta Ana F. Rojas-Cosi Alexander Fajardo-Loyola Diana León-Luna Isabel Castillo-Quezada Mario Laura-Bejarano Milagros Hilario-Sánchez Marco Galarza-Pérez Pool Marcos-Carbajal Hospital effluents as a reservoir of beta-lactamase- and carbapenemase-producing Enterobacteriaceae Revista Peruana de Medicina Experimental y Salud Pública resistencia bacteriana farmacorresistencia bacteriana múltiple antimicrobianos aguas residuales alcantarillado salud pública hospitales públicos perú |
author_facet |
David R. Soriano-Moreno José Yareta Ana F. Rojas-Cosi Alexander Fajardo-Loyola Diana León-Luna Isabel Castillo-Quezada Mario Laura-Bejarano Milagros Hilario-Sánchez Marco Galarza-Pérez Pool Marcos-Carbajal |
author_sort |
David R. Soriano-Moreno |
title |
Hospital effluents as a reservoir of beta-lactamase- and carbapenemase-producing Enterobacteriaceae |
title_short |
Hospital effluents as a reservoir of beta-lactamase- and carbapenemase-producing Enterobacteriaceae |
title_full |
Hospital effluents as a reservoir of beta-lactamase- and carbapenemase-producing Enterobacteriaceae |
title_fullStr |
Hospital effluents as a reservoir of beta-lactamase- and carbapenemase-producing Enterobacteriaceae |
title_full_unstemmed |
Hospital effluents as a reservoir of beta-lactamase- and carbapenemase-producing Enterobacteriaceae |
title_sort |
hospital effluents as a reservoir of beta-lactamase- and carbapenemase-producing enterobacteriaceae |
publisher |
Instituto Nacional de Salud |
series |
Revista Peruana de Medicina Experimental y Salud Pública |
issn |
1726-4634 1726-4642 |
publishDate |
2021-08-01 |
description |
The aim of this study was to determine the presence of beta-lactamase- (bla) producing Enterobacteriaceae in hospital effluent samples from two level II and III hospitals in Lima, Peru. The resistance profile of the isolated bacteria was identified and characterized using the MicroScan system for 18 antimicrobials, and the presence of extended spectrum beta-lactamases (ESBL) (blaCTX-M, blaSHV blaTEM, blaPER) and carbapenemases (blaKPC, blaNDM, blaVIM, blaIMP) resistance genes was determined by conventional PCR. Thirty-two isolates were identified (20 Enterobacteriaceae and 12 gram-negative bacteria). All the isolated bacteria showed multidrug resistance. ESBL (blaTEM) and carbapenemase (blaKPC, blaIMP) genes were found in samples from the hospitals that we evaluated. The release of these microorganisms to public areas and the lack of treatment of the hospital effluents could be an important public health problem. |
topic |
resistencia bacteriana farmacorresistencia bacteriana múltiple antimicrobianos aguas residuales alcantarillado salud pública hospitales públicos perú |
url |
https://rpmesp.ins.gob.pe/rpmesp/article/view/6202 |
work_keys_str_mv |
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