Colocalization of the (Pro)renin Receptor/Atp6ap2 with H+-ATPases in Mouse Kidney but Prorenin Does Not Acutely Regulate Intercalated Cell H+-ATPase Activity.

The (Pro)renin receptor (P)RR/Atp6ap2 is a cell surface protein capable of binding and non-proteolytically activate prorenin. Additionally, (P)RR is associated with H(+)-ATPases and alternative functions in H(+)-ATPase regulation as well as in Wnt signalling have been reported. Kidneys express very...

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Bibliographic Details
Main Authors: Arezoo Daryadel, Soline Bourgeois, Marta F L Figueiredo, Ana Gomes Moreira, Nicole B Kampik, Lisa Oberli, Nilufar Mohebbi, Xifeng Lu, Marcel E Meima, A H Jan Danser, Carsten A Wagner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4732657?pdf=render