Posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in mice

Innate and learned fear can induce rapid changes in body temperature of mammals. The authors identify the posterior subthalamic nucleus as a major thermoregulatory hub that connects the external lateral parabrachial subnucleus to the nucleus of the solitary tract to mediate fear-evoked hypothermia.

Bibliographic Details
Main Authors: Can Liu, Chia-Ying Lee, Greg Asher, Liqin Cao, Yuka Terakoshi, Peng Cao, Reiko Kobayakawa, Ko Kobayakawa, Katsuyasu Sakurai, Qinghua Liu
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22914-6
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spelling doaj-e66d96060c934964b526a8a5331823db2021-05-11T14:49:43ZengNature Publishing GroupNature Communications2041-17232021-05-0112111510.1038/s41467-021-22914-6Posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in miceCan Liu0Chia-Ying Lee1Greg Asher2Liqin Cao3Yuka Terakoshi4Peng Cao5Reiko Kobayakawa6Ko Kobayakawa7Katsuyasu Sakurai8Qinghua Liu9Peking University–Tsinghua University–NIBS Joint Graduate Program, School of Life Sciences, Tsinghua UniversityInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of TsukubaInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of TsukubaInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of TsukubaInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of TsukubaNational Institute of Biological Sciences (NIBS)Department of Functional Neuroscience, Institute of Biomedical Science, Kansai Medical UniversityDepartment of Functional Neuroscience, Institute of Biomedical Science, Kansai Medical UniversityInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of TsukubaNational Institute of Biological Sciences (NIBS)Innate and learned fear can induce rapid changes in body temperature of mammals. The authors identify the posterior subthalamic nucleus as a major thermoregulatory hub that connects the external lateral parabrachial subnucleus to the nucleus of the solitary tract to mediate fear-evoked hypothermia.https://doi.org/10.1038/s41467-021-22914-6
collection DOAJ
language English
format Article
sources DOAJ
author Can Liu
Chia-Ying Lee
Greg Asher
Liqin Cao
Yuka Terakoshi
Peng Cao
Reiko Kobayakawa
Ko Kobayakawa
Katsuyasu Sakurai
Qinghua Liu
spellingShingle Can Liu
Chia-Ying Lee
Greg Asher
Liqin Cao
Yuka Terakoshi
Peng Cao
Reiko Kobayakawa
Ko Kobayakawa
Katsuyasu Sakurai
Qinghua Liu
Posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in mice
Nature Communications
author_facet Can Liu
Chia-Ying Lee
Greg Asher
Liqin Cao
Yuka Terakoshi
Peng Cao
Reiko Kobayakawa
Ko Kobayakawa
Katsuyasu Sakurai
Qinghua Liu
author_sort Can Liu
title Posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in mice
title_short Posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in mice
title_full Posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in mice
title_fullStr Posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in mice
title_full_unstemmed Posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in mice
title_sort posterior subthalamic nucleus (psth) mediates innate fear-associated hypothermia in mice
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-05-01
description Innate and learned fear can induce rapid changes in body temperature of mammals. The authors identify the posterior subthalamic nucleus as a major thermoregulatory hub that connects the external lateral parabrachial subnucleus to the nucleus of the solitary tract to mediate fear-evoked hypothermia.
url https://doi.org/10.1038/s41467-021-22914-6
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