Apocynin Attenuates Cobalt Chloride-Induced Pheochromocytoma Cell Apoptosis by Inhibiting P38-MAPK/Caspase-3 Pathway

Apocynin Attenuates Cobalt Chloride-Induced Pheochromocytoma Cell Apoptosis by Inhibiting P38-MAPK/Caspase-3 Pathway

Background/Aims: Apocynin, a nicotinamide adenine dinucleotide phosphate (NADPH) oxidase inhibitor, has been identified as a potential neuroprotectant. In this study, we aimed to investigate the protective effect of apocynin against cobalt chloride (CoCl2)-induced pheochromocytoma (PC12) cell apopto...

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Bibliographic Details
Main Authors: Jie  Liu, Yuzhang Zhu, Shipiao Chen, Bin Shen, Fang Yu, Yi Zhang, Ruilin Shen
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Apocynin
NADPH oxidase
Cobalt chloride
Pheochromocytoma cell
p38-MAPK
Caspase-3
Apoptosis
Online Access:https://www.karger.com/Article/FullText/491720

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