A rare cause of precocious puberty: Juvenile granulosa cell tumor

• Main Authors: Elif Burcu Aydın, Zerrin Özçelik, Ayşe Selcan Koç, Yılmaz Kor, Ayşe Özkan
• Format: Article
• Language: English
• Published: Journal of Surgery and Medicine 2020-02-01
• Series: Journal of Surgery and Medicine
• Subjects: juvenil granüloza hücreli tümör; over; puberte; juvenile granulosa cell tumor; ovary; puberty
• Online Access: https://dergipark.org.tr/en/pub/josam/issue/52143/636136

Ovarian sex cord-stromal tumors, including granulosa cell tumors are rare, especially in children. They are classified into juvenile and adult types. Juvenile granulosa cell tumors (JGCT) comprise 5% of all granulosa cell tumors. Precocious pseudo-puberty is a common presentation of these tumors, associated with hormonal changes. We report a rare case of JGCT of the ovary in a 4-year-old girl who presented with breast enlargement and alveolar pigmentation for two months. At her examination she had also an abdominal mass. Based on imagining features and laboratory findings, the diagnosis of the mass was unclear. After surgery, histopathological examination revealed JGCT of the left ovary. Although in most of girls with precocious puberty, the etiology is idiopathic, important causes, such as ovarian tumors like JGCTs must be considered.