Adaptive evolution of complex innovations through stepwise metabolic niche expansion
A fundamental question in evolutionary biology is how complex innovations requiring multiple genetic changes arise. Here the authors provide lines of evidence that changing environments facilitate the adaptive evolution of complex metabolic innovations via stepwise acquisition of single reactions.
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Nature Publishing Group
2016-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms11607 |
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doaj-e6a43caad914438b9b00d707a65292f02021-05-11T10:59:41ZengNature Publishing GroupNature Communications2041-17232016-05-017111010.1038/ncomms11607Adaptive evolution of complex innovations through stepwise metabolic niche expansionBalázs Szappanos0Jonathan Fritzemeier1Bálint Csörgő2Viktória Lázár3Xiaowen Lu4Gergely Fekete5Balázs Bálint6Róbert Herczeg7István Nagy8Richard A. Notebaart9Martin J. Lercher10Csaba Pál11Balázs Papp12Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre of the Hungarian Academy of SciencesDepartment for Computer Science, Heinrich Heine University, Universitätsstraße 1Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre of the Hungarian Academy of SciencesSynthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre of the Hungarian Academy of SciencesDepartment of Bioinformatics (CMBI), Radboud University Medical CentreSynthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre of the Hungarian Academy of SciencesSeqOmics Biotechnology LtdSeqOmics Biotechnology LtdSeqOmics Biotechnology LtdDepartment of Bioinformatics (CMBI), Radboud University Medical CentreDepartment for Computer Science, Heinrich Heine University, Universitätsstraße 1Synthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre of the Hungarian Academy of SciencesSynthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre of the Hungarian Academy of SciencesA fundamental question in evolutionary biology is how complex innovations requiring multiple genetic changes arise. Here the authors provide lines of evidence that changing environments facilitate the adaptive evolution of complex metabolic innovations via stepwise acquisition of single reactions.https://doi.org/10.1038/ncomms11607 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Balázs Szappanos Jonathan Fritzemeier Bálint Csörgő Viktória Lázár Xiaowen Lu Gergely Fekete Balázs Bálint Róbert Herczeg István Nagy Richard A. Notebaart Martin J. Lercher Csaba Pál Balázs Papp |
| spellingShingle |
Balázs Szappanos Jonathan Fritzemeier Bálint Csörgő Viktória Lázár Xiaowen Lu Gergely Fekete Balázs Bálint Róbert Herczeg István Nagy Richard A. Notebaart Martin J. Lercher Csaba Pál Balázs Papp Adaptive evolution of complex innovations through stepwise metabolic niche expansion Nature Communications |
| author_facet |
Balázs Szappanos Jonathan Fritzemeier Bálint Csörgő Viktória Lázár Xiaowen Lu Gergely Fekete Balázs Bálint Róbert Herczeg István Nagy Richard A. Notebaart Martin J. Lercher Csaba Pál Balázs Papp |
| author_sort |
Balázs Szappanos |
| title |
Adaptive evolution of complex innovations through stepwise metabolic niche expansion |
| title_short |
Adaptive evolution of complex innovations through stepwise metabolic niche expansion |
| title_full |
Adaptive evolution of complex innovations through stepwise metabolic niche expansion |
| title_fullStr |
Adaptive evolution of complex innovations through stepwise metabolic niche expansion |
| title_full_unstemmed |
Adaptive evolution of complex innovations through stepwise metabolic niche expansion |
| title_sort |
adaptive evolution of complex innovations through stepwise metabolic niche expansion |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2016-05-01 |
| description |
A fundamental question in evolutionary biology is how complex innovations requiring multiple genetic changes arise. Here the authors provide lines of evidence that changing environments facilitate the adaptive evolution of complex metabolic innovations via stepwise acquisition of single reactions. |
| url |
https://doi.org/10.1038/ncomms11607 |
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