Protective Effects of 18β-Glycyrrhetinic Acid on Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats

Protective Effects of 18β-Glycyrrhetinic Acid on Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats

Pulmonary arterial hypertension (PAH) is a destructive and rare disorder characterized by a progressive increase in pulmonary artery pressure and vasoconstriction, ultimately leading to right ventricular failure and death. 18β-Glycyrrhetinic acid (18β-GA) is an active ingredient in the commonly used...

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Bibliographic Details
Main Authors: Min Zhang, Zhi Chang, Fang Zhao, Peng Zhang, Yin-Ju Hao, Lin Yan, Ning Liu, Jun-Li Wang, Lei Bo, Ping Ma, Wei Zhou, Xuan Ma, Qing-Bin Xu, Ru Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Pharmacology
Subjects:
pulmonary arterial hypertension
monocrotaline
18β-glycyrrhetinic acid
oxidative stress
nicotinamide adenine dinucleotide phosphate oxidase
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00013/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.00013/full

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