Investigation of Proteomic and Phosphoproteomic Responses to Signaling Network Perturbations Reveals Functional Pathway Organizations in Yeast
Summary: Governance of protein phosphorylation by kinases and phosphatases constitutes an essential regulatory network in eukaryotic cells. Network dysregulation leads to severe consequences and is often a key factor in disease pathogenesis. Previous studies revealed multiple roles for protein phosp...
Main Authors: | Jiaming Li, Joao A. Paulo, David P. Nusinow, Edward L. Huttlin, Steven P. Gygi |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2019-11-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124719313348 |
Similar Items
-
Quantitative Phosphoproteomics Reveals the Signaling Dynamics of Cell-Cycle Kinases in the Fission Yeast Schizosaccharomyces pombe
by: Matthew P. Swaffer, et al.
Published: (2018-07-01) -
Developmentally-Dynamic Murine Brain Proteomes and Phosphoproteomes Revealed by Quantitative Proteomics
by: Peter F. Doubleday, et al.
Published: (2014-04-01) -
Proteomics and phosphoproteomics applied to cell signaling and cancer
by: D'souza, Rochelle
Published: (2013) -
Phosphoproteomic analyses reveal signaling pathways that facilitate lytic gammaherpesvirus replication.
by: James A Stahl, et al.
Published: (2013-09-01) -
Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast
by: Noah Dephoure, et al.
Published: (2014-07-01)