Fundus Autofluorescence and Spectral Domain OCT in Central Serous Chorioretinopathy
Background. To describe the standard autofluorescence (FAF), the near infrared autofluorescence (NIA) and optical coherence tomography (OCT) patterns in central serous chorioretinopathy, correlating them with fluorescein angiography. Methods. Cross-sectional observational study, in which patients wi...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2011-01-01
|
Series: | Journal of Ophthalmology |
Online Access: | http://dx.doi.org/10.1155/2011/706849 |
id |
doaj-e6d2592711d8413aa76b9a09ee6ec970 |
---|---|
record_format |
Article |
spelling |
doaj-e6d2592711d8413aa76b9a09ee6ec9702020-11-24T22:39:00ZengHindawi LimitedJournal of Ophthalmology2090-004X2090-00582011-01-01201110.1155/2011/706849706849Fundus Autofluorescence and Spectral Domain OCT in Central Serous ChorioretinopathyLuiz Roisman0Daniel Lavinsky1Fernanda Magalhaes2Fabio Bom Aggio3Nilva Moraes4Jose A. Cardillo5Michel E. Farah6Department of Ophthalmology, Federal University of São Paulo, Paulista School of Medicine, 04025-011 São Paulo, SP, BrazilDepartment of Ophthalmology, Federal University of São Paulo, Paulista School of Medicine, 04025-011 São Paulo, SP, BrazilDepartment of Ophthalmology, Federal University of São Paulo, Paulista School of Medicine, 04025-011 São Paulo, SP, BrazilDepartment of Ophthalmology, Federal University of São Paulo, Paulista School of Medicine, 04025-011 São Paulo, SP, BrazilDepartment of Ophthalmology, Federal University of São Paulo, Paulista School of Medicine, 04025-011 São Paulo, SP, BrazilDepartment of Ophthalmology, Federal University of São Paulo, Paulista School of Medicine, 04025-011 São Paulo, SP, BrazilDepartment of Ophthalmology, Federal University of São Paulo, Paulista School of Medicine, 04025-011 São Paulo, SP, BrazilBackground. To describe the standard autofluorescence (FAF), the near infrared autofluorescence (NIA) and optical coherence tomography (OCT) patterns in central serous chorioretinopathy, correlating them with fluorescein angiography. Methods. Cross-sectional observational study, in which patients with at least seven months of CSC underwent ophthalmologic examination, fundus photography, FAF, NIA, fluorescein angiography (FA), and spectral-domain OCT. Results. Seventeen eyes of thirteen patients were included. The presentation features were a mottled hyperFAF in the detached area and areas with pigment mottling. NIA images showed areas of hyperNIA similar to FAF and localized areas of hypoNIA, which correlated with the points of leakage in the FA. OCT showed pigment epithelium detachment at the location of these hypoNIA spots. Discussion. FAF showed increased presence of fluorophores in the area of retinal detachment, which is believed to appear secondary to lipofuscin accumulation in the RPE or the presence of debris in the subretinal fluid. NIA has been related to the choroidal melanin content and there were areas of both increased and decreased NIA, which could be explained by damage ahead the retina, basically RPE and choroid. These findings, along with the PEDs found in the areas of hypoNIA, support the notion of a primary choroidal disease in CSC.http://dx.doi.org/10.1155/2011/706849 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Luiz Roisman Daniel Lavinsky Fernanda Magalhaes Fabio Bom Aggio Nilva Moraes Jose A. Cardillo Michel E. Farah |
spellingShingle |
Luiz Roisman Daniel Lavinsky Fernanda Magalhaes Fabio Bom Aggio Nilva Moraes Jose A. Cardillo Michel E. Farah Fundus Autofluorescence and Spectral Domain OCT in Central Serous Chorioretinopathy Journal of Ophthalmology |
author_facet |
Luiz Roisman Daniel Lavinsky Fernanda Magalhaes Fabio Bom Aggio Nilva Moraes Jose A. Cardillo Michel E. Farah |
author_sort |
Luiz Roisman |
title |
Fundus Autofluorescence and Spectral Domain OCT in Central Serous Chorioretinopathy |
title_short |
Fundus Autofluorescence and Spectral Domain OCT in Central Serous Chorioretinopathy |
title_full |
Fundus Autofluorescence and Spectral Domain OCT in Central Serous Chorioretinopathy |
title_fullStr |
Fundus Autofluorescence and Spectral Domain OCT in Central Serous Chorioretinopathy |
title_full_unstemmed |
Fundus Autofluorescence and Spectral Domain OCT in Central Serous Chorioretinopathy |
title_sort |
fundus autofluorescence and spectral domain oct in central serous chorioretinopathy |
publisher |
Hindawi Limited |
series |
Journal of Ophthalmology |
issn |
2090-004X 2090-0058 |
publishDate |
2011-01-01 |
description |
Background. To describe the standard autofluorescence (FAF), the near infrared autofluorescence (NIA) and optical coherence tomography (OCT) patterns in central serous chorioretinopathy, correlating them with fluorescein angiography. Methods. Cross-sectional observational study, in which patients with at least seven months of CSC underwent ophthalmologic examination, fundus photography, FAF, NIA, fluorescein angiography (FA), and spectral-domain OCT. Results. Seventeen eyes of thirteen patients were included. The presentation features were a mottled hyperFAF in the detached area and areas with pigment mottling. NIA images showed areas of hyperNIA similar to FAF and localized areas of hypoNIA, which correlated with the points of leakage in the FA. OCT showed pigment epithelium detachment at the location of these hypoNIA spots. Discussion. FAF showed increased presence of fluorophores in the area of retinal detachment, which is believed to appear secondary to lipofuscin accumulation in the RPE or the presence of debris in the subretinal fluid. NIA has been related to the choroidal melanin content and there were areas of both increased and decreased NIA, which could be explained by damage ahead the retina, basically RPE and choroid. These findings, along with the PEDs found in the areas of hypoNIA, support the notion of a primary choroidal disease in CSC. |
url |
http://dx.doi.org/10.1155/2011/706849 |
work_keys_str_mv |
AT luizroisman fundusautofluorescenceandspectraldomainoctincentralserouschorioretinopathy AT daniellavinsky fundusautofluorescenceandspectraldomainoctincentralserouschorioretinopathy AT fernandamagalhaes fundusautofluorescenceandspectraldomainoctincentralserouschorioretinopathy AT fabiobomaggio fundusautofluorescenceandspectraldomainoctincentralserouschorioretinopathy AT nilvamoraes fundusautofluorescenceandspectraldomainoctincentralserouschorioretinopathy AT joseacardillo fundusautofluorescenceandspectraldomainoctincentralserouschorioretinopathy AT michelefarah fundusautofluorescenceandspectraldomainoctincentralserouschorioretinopathy |
_version_ |
1725710662398640128 |