Localized eosinophilic fasciitis (Shulman’s disease) as a differential diagnosis of nerve compression syndrome
A 46-year-old man presented with clinical signs of nerve compression syndrome of his right ulnar nerve as confirmed by nerve conduction studies. Unexpectedly, clinical examination and magnetic resonance imaging (MRI) revealed a subcutaneous tumor of 5×2 cm above the ulnar groove. Surgical exploratio...
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doaj-e6e57214e1c04a5896d65a69a375d3592021-09-05T20:51:10ZengDe GruyterInnovative Surgical Science2364-74852017-03-0121232510.1515/iss-2016-0203iss-2016-0203Localized eosinophilic fasciitis (Shulman’s disease) as a differential diagnosis of nerve compression syndromeThönnes Simon0Sorg Heiko1Hauser Jörg2Tilkorn Daniel J.3Department of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Alfried Krupp Krankenhaus Essen, Hellweg 100, 45276 Essen, Germany, simon.thoennes@krupp-krankenhaus.deDepartment of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Alfried Krupp Krankenhaus Essen, Essen, GermanyDepartment of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Alfried Krupp Krankenhaus Essen, Essen, GermanyDepartment of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Alfried Krupp Krankenhaus Essen, Essen, GermanyA 46-year-old man presented with clinical signs of nerve compression syndrome of his right ulnar nerve as confirmed by nerve conduction studies. Unexpectedly, clinical examination and magnetic resonance imaging (MRI) revealed a subcutaneous tumor of 5×2 cm above the ulnar groove. Surgical exploration and histopathology of biopsies demonstrated the nerve distended and entrapped into an eosinophilic, inflammatory tissue. This rare condition is consistent with localized eosinophilic fasciitis, with no systemic manifestations. There are reports of isolated forearm versions of the disease. However, none occurred with the entrapment of a peripheral nerve appearing as a peripheral nerve tumor, yet. Consequentially, the presented patient would not have benefitted from further surgical neurolysis or tumor debulking, as eosinophilic fasciitis is an inflammatory and systemic disease. The patient’s symptoms decreased spontaneously after 4 weeks of postsurgical treatment, including nonsteroidal anti-inflammatory drugs (NSAIDs). Altogether, this case proved the necessity to regard even rare diseases as a potential cause of entrapment of peripheral nerves. This should lead surgeons to critical, differential diagnostic thinking and suggest that systemic diseases may be encountered during surgery due to their capability to mimic peripheral nerve tumors.https://doi.org/10.1515/iss-2016-0203eosinophilic fasciitisnerve compression syndromeperipheral nerve tumorshulman’s disease |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Thönnes Simon Sorg Heiko Hauser Jörg Tilkorn Daniel J. |
spellingShingle |
Thönnes Simon Sorg Heiko Hauser Jörg Tilkorn Daniel J. Localized eosinophilic fasciitis (Shulman’s disease) as a differential diagnosis of nerve compression syndrome Innovative Surgical Science eosinophilic fasciitis nerve compression syndrome peripheral nerve tumor shulman’s disease |
author_facet |
Thönnes Simon Sorg Heiko Hauser Jörg Tilkorn Daniel J. |
author_sort |
Thönnes Simon |
title |
Localized eosinophilic fasciitis (Shulman’s disease) as a differential diagnosis of nerve compression syndrome |
title_short |
Localized eosinophilic fasciitis (Shulman’s disease) as a differential diagnosis of nerve compression syndrome |
title_full |
Localized eosinophilic fasciitis (Shulman’s disease) as a differential diagnosis of nerve compression syndrome |
title_fullStr |
Localized eosinophilic fasciitis (Shulman’s disease) as a differential diagnosis of nerve compression syndrome |
title_full_unstemmed |
Localized eosinophilic fasciitis (Shulman’s disease) as a differential diagnosis of nerve compression syndrome |
title_sort |
localized eosinophilic fasciitis (shulman’s disease) as a differential diagnosis of nerve compression syndrome |
publisher |
De Gruyter |
series |
Innovative Surgical Science |
issn |
2364-7485 |
publishDate |
2017-03-01 |
description |
A 46-year-old man presented with clinical signs of nerve compression syndrome of his right ulnar nerve as confirmed by nerve conduction studies. Unexpectedly, clinical examination and magnetic resonance imaging (MRI) revealed a subcutaneous tumor of 5×2 cm above the ulnar groove. Surgical exploration and histopathology of biopsies demonstrated the nerve distended and entrapped into an eosinophilic, inflammatory tissue. This rare condition is consistent with localized eosinophilic fasciitis, with no systemic manifestations. There are reports of isolated forearm versions of the disease. However, none occurred with the entrapment of a peripheral nerve appearing as a peripheral nerve tumor, yet. Consequentially, the presented patient would not have benefitted from further surgical neurolysis or tumor debulking, as eosinophilic fasciitis is an inflammatory and systemic disease. The patient’s symptoms decreased spontaneously after 4 weeks of postsurgical treatment, including nonsteroidal anti-inflammatory drugs (NSAIDs). Altogether, this case proved the necessity to regard even rare diseases as a potential cause of entrapment of peripheral nerves. This should lead surgeons to critical, differential diagnostic thinking and suggest that systemic diseases may be encountered during surgery due to their capability to mimic peripheral nerve tumors. |
topic |
eosinophilic fasciitis nerve compression syndrome peripheral nerve tumor shulman’s disease |
url |
https://doi.org/10.1515/iss-2016-0203 |
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