Dysregulation of tristetraprolin and human antigen R promotes gastric cancer progressions partly by upregulation of the high-mobility group box 1

Dysregulation of tristetraprolin and human antigen R promotes gastric cancer progressions partly by upregulation of the high-mobility group box 1

Abstract Aberrant expression of ARE-binding proteins (ARE-BPs) plays an important role in several diseases, including cancer. Both tristetraprolin (TTP) and human antigen R (HuR) are important ARE-BPs and always play opposite roles in regulating target mRNAs. Our previous work has demonstrated that...

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Bibliographic Details
Main Authors: Hao Wang, Yigang Chen, Jian Guo, Ting Shan, Kaiyuan Deng, Jialin Chen, Liping Cai, Hong Zhou, Qin Zhao, Shimao Jin, Jiazeng Xia
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25443-3

Internet

https://doi.org/10.1038/s41598-018-25443-3

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