Assessing the Diversity of the Form of Age-Specific Changes in Adult Mortality from Captive Mammalian Populations
Actuarial senescence (i.e., the age-specific increase in mortality rate) is pervasive across mammalian species, but our current understanding of the diversity of forms that actuarial senescence displays across species remains limited. Although several mathematical models have been proposed to model...
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doaj-e6ef220152b3405c83c1a39d0f89fa382020-11-25T01:25:59ZengMDPI AGDiversity1424-28182020-09-011235435410.3390/d12090354Assessing the Diversity of the Form of Age-Specific Changes in Adult Mortality from Captive Mammalian PopulationsVictor Ronget0Jean-François Lemaître1Morgane Tidière2Jean-Michel Gaillard3Unité Eco-anthropologie (EA), Muséum National d’Histoire Naturelle, CNRS, Université Paris Diderot, F-75016 Paris, FranceLaboratoire de Biométrie et Biologie Évolutive UMR 5558, Univ Lyon, Université Lyon 1, CNRS, F-69622 Villeurbanne, FranceSpecies360 Conservation Science Alliance, Bloomington, MN 55425, USALaboratoire de Biométrie et Biologie Évolutive UMR 5558, Univ Lyon, Université Lyon 1, CNRS, F-69622 Villeurbanne, FranceActuarial senescence (i.e., the age-specific increase in mortality rate) is pervasive across mammalian species, but our current understanding of the diversity of forms that actuarial senescence displays across species remains limited. Although several mathematical models have been proposed to model actuarial senescence, there is still no consensus on which model to use, especially when comparing mortality patterns among species. To fill this knowledge gap, we fitted and compared different forms of increase using models commonly used in senescence studies (i.e., Gompertz, Weibull, and logistic) across 61 species of mammalian captive populations using the Bayesian Survival Trajectory Analysis (BaSTA) approach. For as much as 79% of the species, a Gompertz increase of mortality with age was the most parsimonious model that satisfactorily described the shape of age-specific mortality changes in adults. This highlights that the form of the increase in mortality is mostly consistent across mammalian species and follows the Gompertz rule with some rare exceptions. The implications of that result are twofold. First, the Gompertz rate of mortality increase should be used in cross-species comparative analyses of mammals, as already done in some studies. Second, although the Gompertz model accurately describes actuarial senescence in most mammals, there are notable exceptions, and the factors causing this deviation from an exponential mortality increase during the adult stage warrant further investigation.https://www.mdpi.com/1424-2818/12/9/354agingsenescencedemographyBayesian analysispopulation dynamics |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Victor Ronget Jean-François Lemaître Morgane Tidière Jean-Michel Gaillard |
spellingShingle |
Victor Ronget Jean-François Lemaître Morgane Tidière Jean-Michel Gaillard Assessing the Diversity of the Form of Age-Specific Changes in Adult Mortality from Captive Mammalian Populations Diversity aging senescence demography Bayesian analysis population dynamics |
author_facet |
Victor Ronget Jean-François Lemaître Morgane Tidière Jean-Michel Gaillard |
author_sort |
Victor Ronget |
title |
Assessing the Diversity of the Form of Age-Specific Changes in Adult Mortality from Captive Mammalian Populations |
title_short |
Assessing the Diversity of the Form of Age-Specific Changes in Adult Mortality from Captive Mammalian Populations |
title_full |
Assessing the Diversity of the Form of Age-Specific Changes in Adult Mortality from Captive Mammalian Populations |
title_fullStr |
Assessing the Diversity of the Form of Age-Specific Changes in Adult Mortality from Captive Mammalian Populations |
title_full_unstemmed |
Assessing the Diversity of the Form of Age-Specific Changes in Adult Mortality from Captive Mammalian Populations |
title_sort |
assessing the diversity of the form of age-specific changes in adult mortality from captive mammalian populations |
publisher |
MDPI AG |
series |
Diversity |
issn |
1424-2818 |
publishDate |
2020-09-01 |
description |
Actuarial senescence (i.e., the age-specific increase in mortality rate) is pervasive across mammalian species, but our current understanding of the diversity of forms that actuarial senescence displays across species remains limited. Although several mathematical models have been proposed to model actuarial senescence, there is still no consensus on which model to use, especially when comparing mortality patterns among species. To fill this knowledge gap, we fitted and compared different forms of increase using models commonly used in senescence studies (i.e., Gompertz, Weibull, and logistic) across 61 species of mammalian captive populations using the Bayesian Survival Trajectory Analysis (BaSTA) approach. For as much as 79% of the species, a Gompertz increase of mortality with age was the most parsimonious model that satisfactorily described the shape of age-specific mortality changes in adults. This highlights that the form of the increase in mortality is mostly consistent across mammalian species and follows the Gompertz rule with some rare exceptions. The implications of that result are twofold. First, the Gompertz rate of mortality increase should be used in cross-species comparative analyses of mammals, as already done in some studies. Second, although the Gompertz model accurately describes actuarial senescence in most mammals, there are notable exceptions, and the factors causing this deviation from an exponential mortality increase during the adult stage warrant further investigation. |
topic |
aging senescence demography Bayesian analysis population dynamics |
url |
https://www.mdpi.com/1424-2818/12/9/354 |
work_keys_str_mv |
AT victorronget assessingthediversityoftheformofagespecificchangesinadultmortalityfromcaptivemammalianpopulations AT jeanfrancoislemaitre assessingthediversityoftheformofagespecificchangesinadultmortalityfromcaptivemammalianpopulations AT morganetidiere assessingthediversityoftheformofagespecificchangesinadultmortalityfromcaptivemammalianpopulations AT jeanmichelgaillard assessingthediversityoftheformofagespecificchangesinadultmortalityfromcaptivemammalianpopulations |
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