Protein arginine methyltransferase 3-induced metabolic reprogramming is a vulnerable target of pancreatic cancer

Protein arginine methyltransferase 3-induced metabolic reprogramming is a vulnerable target of pancreatic cancer

Abstract Background The biological function of protein arginine methyltransferase 3 (PRMT3) is not well known because very few physiological substrates of this methyltransferase have been identified to date. Methods The clinical significance of PRMT3 in pancreatic cancer was studied by database anal...

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Bibliographic Details
Main Authors: Ming-Chuan Hsu, Ya-Li Tsai, Chia-Hsien Lin, Mei-Ren Pan, Yan-Shen Shan, Tsung-Yen Cheng, Skye Hung-Chun Cheng, Li-Tzong Chen, Wen-Chun Hung
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Hematology & Oncology
Subjects:
Protein arginine methyltransferase 3
Methylation
Glyceraldehyde-3-phosphate dehydrogenase
Metabolic reprogramming
Online Access:http://link.springer.com/article/10.1186/s13045-019-0769-7

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