Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast

Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast

Summary: CDH1 and PIK3CA are the two most frequently mutated genes in invasive lobular carcinoma (ILC) of the breast. Transcription profiling has identified molecular subtypes for ILC, one of which, immune-related (IR), is associated with gene expression linked to lymphocyte and macrophage infiltrat...

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Main Authors: Yeji An, Jessica R. Adams, Daniel P. Hollern, Anthony Zhao, Stephen G. Chang, Miki S. Gams, Philip E.D. Chung, Xiaping He, Rhea Jangra, Juhi S. Shah, Joanna Yang, Lauren A. Beck, Nandini Raghuram, Katelyn J. Kozma, Amanda J. Loch, Wei Wang, Cheng Fan, Susan J. Done, Eldad Zacksenhaus, Cynthia J. Guidos, Charles M. Perou, Sean E. Egan
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718315018

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http://www.sciencedirect.com/science/article/pii/S2211124718315018

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