Reassembly of JIP1 scaffold complex in JNK MAP kinase pathway using heterologous protein interactions.

Formation of signaling protein complexes is crucial for proper signal transduction. Scaffold proteins in MAP kinase pathways are thought to facilitate complex assembly, thereby promoting efficient and specific signaling. To elucidate the assembly mechanism of scaffold complexes in mammals, we attemp...

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Bibliographic Details
Main Authors: Jiyoung Moon, Sang-Hyun Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4016011?pdf=render