Post-treatment work patterns amongst survivors of lymphoma treated with high-dose chemotherapy with autologous stem-cell transplantation

Abstract Background This study describes post-treatment work patterns in lymphoma survivors treated with high-dose chemotherapy with autologous stem-cell transplantation (HDT-ASCT). It aims to identify determinants for labour force participation and exclusion after HDT-ASCT. Methods All survivors tr...

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Main Authors: Kjersti Helene Hernæs, Knut B. Smeland, Unn-Merete Fagerli, Cecilie E. Kiserud
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-021-07836-2
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spelling doaj-e71672dd2dcb42dcae7f3d993f4a00a52021-02-14T12:48:39ZengBMCBMC Cancer1471-24072021-02-0121111110.1186/s12885-021-07836-2Post-treatment work patterns amongst survivors of lymphoma treated with high-dose chemotherapy with autologous stem-cell transplantationKjersti Helene Hernæs0Knut B. Smeland1Unn-Merete Fagerli2Cecilie E. Kiserud3Norwegian Institute of Public HealthNational Advisory Unit for Late Effects after Cancer Treatment, Oslo University HospitalDepartment of Oncology, St. Olavs hospital HFNational Advisory Unit for Late Effects after Cancer Treatment, Oslo University HospitalAbstract Background This study describes post-treatment work patterns in lymphoma survivors treated with high-dose chemotherapy with autologous stem-cell transplantation (HDT-ASCT). It aims to identify determinants for labour force participation and exclusion after HDT-ASCT. Methods All survivors treated with HDT-ASCT for lymphoma in Norway between 1995 and 2008, aged ≥18 years at HDT-ASCT and alive at survey in 2012–2013 were eligible. We divide survivors by current employment status (full-time, part-time and unemployed). Main outcomes are current employment status, work hours and work ability. Withdrawals are patients employed when diagnosed but not before HDT-ASCT. Results Of the 274 who completed the survey, 82% (N = 225) were included in the final analyses. Mean age at survey was 52 years, 39% were female, 85% were employed when diagnosed, 77% before HDT-ASCT and 69% at survey. Employment before HDT-ASCT corresponds with a higher probability of employment at survey for a given symptom burden. In the most extensive statistical model, it increases with 37.3 percentage points. Work hours amongst withdrawals plummet after HDT-ASCT while work ability shows a rebound effect. The potential economic gain from their re-enter into the work force equals 70% of the average annual wage in Norway in 2012. Conclusions For a given symptom burden, staying employed throughout diagnosis and treatment is associated with a higher probability of future employment. These results favour policies for labour force inclusion past diagnosis and treatment increasing cancer survivors’ probability of future employment. However, we need more research on withdrawal mechanisms, and on policy measures that promote inclusion.https://doi.org/10.1186/s12885-021-07836-2LymphomaHDT-ASCTLate effectsEmploymentWork abilityWithdrawal
collection DOAJ
language English
format Article
sources DOAJ
author Kjersti Helene Hernæs
Knut B. Smeland
Unn-Merete Fagerli
Cecilie E. Kiserud
spellingShingle Kjersti Helene Hernæs
Knut B. Smeland
Unn-Merete Fagerli
Cecilie E. Kiserud
Post-treatment work patterns amongst survivors of lymphoma treated with high-dose chemotherapy with autologous stem-cell transplantation
BMC Cancer
Lymphoma
HDT-ASCT
Late effects
Employment
Work ability
Withdrawal
author_facet Kjersti Helene Hernæs
Knut B. Smeland
Unn-Merete Fagerli
Cecilie E. Kiserud
author_sort Kjersti Helene Hernæs
title Post-treatment work patterns amongst survivors of lymphoma treated with high-dose chemotherapy with autologous stem-cell transplantation
title_short Post-treatment work patterns amongst survivors of lymphoma treated with high-dose chemotherapy with autologous stem-cell transplantation
title_full Post-treatment work patterns amongst survivors of lymphoma treated with high-dose chemotherapy with autologous stem-cell transplantation
title_fullStr Post-treatment work patterns amongst survivors of lymphoma treated with high-dose chemotherapy with autologous stem-cell transplantation
title_full_unstemmed Post-treatment work patterns amongst survivors of lymphoma treated with high-dose chemotherapy with autologous stem-cell transplantation
title_sort post-treatment work patterns amongst survivors of lymphoma treated with high-dose chemotherapy with autologous stem-cell transplantation
publisher BMC
series BMC Cancer
issn 1471-2407
publishDate 2021-02-01
description Abstract Background This study describes post-treatment work patterns in lymphoma survivors treated with high-dose chemotherapy with autologous stem-cell transplantation (HDT-ASCT). It aims to identify determinants for labour force participation and exclusion after HDT-ASCT. Methods All survivors treated with HDT-ASCT for lymphoma in Norway between 1995 and 2008, aged ≥18 years at HDT-ASCT and alive at survey in 2012–2013 were eligible. We divide survivors by current employment status (full-time, part-time and unemployed). Main outcomes are current employment status, work hours and work ability. Withdrawals are patients employed when diagnosed but not before HDT-ASCT. Results Of the 274 who completed the survey, 82% (N = 225) were included in the final analyses. Mean age at survey was 52 years, 39% were female, 85% were employed when diagnosed, 77% before HDT-ASCT and 69% at survey. Employment before HDT-ASCT corresponds with a higher probability of employment at survey for a given symptom burden. In the most extensive statistical model, it increases with 37.3 percentage points. Work hours amongst withdrawals plummet after HDT-ASCT while work ability shows a rebound effect. The potential economic gain from their re-enter into the work force equals 70% of the average annual wage in Norway in 2012. Conclusions For a given symptom burden, staying employed throughout diagnosis and treatment is associated with a higher probability of future employment. These results favour policies for labour force inclusion past diagnosis and treatment increasing cancer survivors’ probability of future employment. However, we need more research on withdrawal mechanisms, and on policy measures that promote inclusion.
topic Lymphoma
HDT-ASCT
Late effects
Employment
Work ability
Withdrawal
url https://doi.org/10.1186/s12885-021-07836-2
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