Influence of Magnesium on the Deposition of Cadmium in Rats

Magnesium chloride was given via drinking water (500 mg Mg/L) to rats exposed intragastrically to cadmium (cadmium 109) at a dose corresponding to 10 mg/kg diet for 7, 14, 21, and 28 d. The results provided the evidence that magnesium decreased cadmium retention in the duodenum, kidneys, and liver a...

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Main Author: Grosicki Andrzej
Format: Article
Language:English
Published: Sciendo 2012-12-01
Series:Bulletin of the Veterinary Institute in Pulawy
Subjects:
rat
Online Access:https://doi.org/10.2478/v10213-012-0104-3
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spelling doaj-e716ca6d807c48488ac5b0cc1618ba642021-09-22T06:13:29ZengSciendoBulletin of the Veterinary Institute in Pulawy2300-32352012-12-0156459159410.2478/v10213-012-0104-3Influence of Magnesium on the Deposition of Cadmium in RatsGrosicki Andrzej0Laboratory of Radiological Protection and Isotopic Research, National Veterinary Research Institute. 24-100Pulawy, PolandMagnesium chloride was given via drinking water (500 mg Mg/L) to rats exposed intragastrically to cadmium (cadmium 109) at a dose corresponding to 10 mg/kg diet for 7, 14, 21, and 28 d. The results provided the evidence that magnesium decreased cadmium retention in the duodenum, kidneys, and liver after 7 d. Significant reduction in cadmium retention was also found on days 14 d and 21 in kidneys. No significant decreases in cadmium retention in the organs examined were noted after 28 d. The results suggest that beneficial action of magnesium on body cadmium accumulation ceased with time after the two metal administration.https://doi.org/10.2478/v10213-012-0104-3ratcadmiummagnesiuminteraction
collection DOAJ
language English
format Article
sources DOAJ
author Grosicki Andrzej
spellingShingle Grosicki Andrzej
Influence of Magnesium on the Deposition of Cadmium in Rats
Bulletin of the Veterinary Institute in Pulawy
rat
cadmium
magnesium
interaction
author_facet Grosicki Andrzej
author_sort Grosicki Andrzej
title Influence of Magnesium on the Deposition of Cadmium in Rats
title_short Influence of Magnesium on the Deposition of Cadmium in Rats
title_full Influence of Magnesium on the Deposition of Cadmium in Rats
title_fullStr Influence of Magnesium on the Deposition of Cadmium in Rats
title_full_unstemmed Influence of Magnesium on the Deposition of Cadmium in Rats
title_sort influence of magnesium on the deposition of cadmium in rats
publisher Sciendo
series Bulletin of the Veterinary Institute in Pulawy
issn 2300-3235
publishDate 2012-12-01
description Magnesium chloride was given via drinking water (500 mg Mg/L) to rats exposed intragastrically to cadmium (cadmium 109) at a dose corresponding to 10 mg/kg diet for 7, 14, 21, and 28 d. The results provided the evidence that magnesium decreased cadmium retention in the duodenum, kidneys, and liver after 7 d. Significant reduction in cadmium retention was also found on days 14 d and 21 in kidneys. No significant decreases in cadmium retention in the organs examined were noted after 28 d. The results suggest that beneficial action of magnesium on body cadmium accumulation ceased with time after the two metal administration.
topic rat
cadmium
magnesium
interaction
url https://doi.org/10.2478/v10213-012-0104-3
work_keys_str_mv AT grosickiandrzej influenceofmagnesiumonthedepositionofcadmiuminrats
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