ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination

Summary: B cell development depends on the coordinated expression and cooperation of several transcription factors. Here we show that the transcription factor ETS-related gene (ERG) is crucial for normal B cell development and that its deletion results in a substantial loss of bone marrow B cell pro...

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Bibliographic Details
Main Authors: Elisabeth Søndergaard, Alexander Rauch, Magali Michaut, Nicolas Rapin, Matilda Rehn, Anna S. Wilhelmson, Alessandro Camponeschi, Marie S. Hasemann, Frederik O. Bagger, Johan Jendholm, Kasper J. Knudsen, Susanne Mandrup, Inga-Lill Mårtensson, Bo T. Porse
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719314317