Histopathology and immunohistochemistry of choroidal melanocytoma demonstrated by local resection: A case report

• Main Authors: Hiroshi Goto, Naoyuki Yamakawa, Hiroyuki Komatsu
• Format: Article
• Language: English
• Published: Elsevier 2021-09-01
• Series: American Journal of Ophthalmology Case Reports
• Subjects: Melanocytoma; Choroid; Histopathology; Local resection
• Online Access: http://www.sciencedirect.com/science/article/pii/S2451993621001560

Purpose: To describe the clinical and histopathological features of a case of choroidal melanocytoma treated by local resection. Observations: A 73-year-old man was referred to our hospital with a clinical diagnosis of choroidal melanoma. His best corrected visual acuity at presentation was 20/20 OU. Ocular fundus examination of his right eye showed a pigmented intraocular tumor. Local resection of the tumor was performed under general anesthesia. Histopathological examination of the excised tumor showed proliferation of round to ovoid cells with abundant cytoplasm containing many melanosomes and uniform nuclei and these histopathological findings were compatible with a diagnosis of choroidal melanocytoma. Visual acuity of 20/200 OD has been maintained for over 4 years without local recurrence. Conclusions and Importance: Clinical diagnosis of choroidal melanocytoma, especially differentiation from melanoma, is difficult and challenging. Local resection of the tumor allowed study of the histopathological features of the choroidal melanocytoma and maintained tolerable vision in the current case.