Long-Term Calorie Restriction Enhances Cellular Quality-Control Processes in Human Skeletal Muscle

Calorie restriction (CR) retards aging, acts as a hormetic intervention, and increases serum corticosterone and HSP70 expression in rodents. However, less is known regarding the effects of CR on these factors in humans. Serum cortisol and molecular chaperones and autophagic proteins were measured in...

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Bibliographic Details
Main Authors: Ling Yang, Danilo Licastro, Edda Cava, Nicola Veronese, Francesco Spelta, Wanda Rizza, Beatrice Bertozzi, Dennis T. Villareal, Gökhan S. Hotamisligil, John O. Holloszy, Luigi Fontana
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715014837