Food insecurity and the risk of depression in people living with HIV/AIDS: a systematic review and meta-analysis
Abstract Background The link between food insecurity and depression in people living with HIV/AIDS (PLWHA) has been explored in numerous studies; however, the existing evidence is inconclusive due to inconsistent results. Therefore, the objective of this systematic review and meta-analysis is to exa...
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doaj-e76d9e4f1d424a4eb5f4e190f6070f5c2020-11-25T03:19:30ZengBMCAIDS Research and Therapy1742-64052020-06-0117111110.1186/s12981-020-00291-2Food insecurity and the risk of depression in people living with HIV/AIDS: a systematic review and meta-analysisGetinet Ayano0Light Tsegay1Melat Solomon2Research and Training Department, Amanuel Mental Specialized Hospital Addis AbabaCollege of Health Sciences, Axum UniversityResearch and Training Department, Amanuel Mental Specialized Hospital Addis AbabaAbstract Background The link between food insecurity and depression in people living with HIV/AIDS (PLWHA) has been explored in numerous studies; however, the existing evidence is inconclusive due to inconsistent results. Therefore, the objective of this systematic review and meta-analysis is to examine the relationship between food insecurity and depression in PLWHA. Methods We systematically searched PubMed, EMBASE, and Scopus to identify relevant studies. A random-effect model was used for conducting the meta-analysis. We assessed the risk of publication bias by funnel plot and Egger’s regression asymmetry test. Results In this review, seven studies were included in the final analysis. Our meta-analysis revealed that food insecurity significantly increased the risk of depression in PLWHA [RR 2.28 (95% CI 1.56–3.32)]. This association remained significant after adjusting for the confounding effects of drug use [RR 1.63 (95% CI 1.27–2.10)], social support [RR 2.21 (95% CI 1.18–4.16)] as well as ART drugs [RR 1.96 (95% CI 1.17–3.28)]. Our subgroup and sensitivity confirmed the robustness of the main analysis. Conclusion This systematic review and meta-analysis suggest a significant association between food insecurity and increased risk of depression PLWHA. Therefore, early screening and management of food insecurity in PLWHA seem to be necessary.http://link.springer.com/article/10.1186/s12981-020-00291-2Food insecurityDepressionHIVAIDSSystematic reviewMeta-analysis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Getinet Ayano Light Tsegay Melat Solomon |
spellingShingle |
Getinet Ayano Light Tsegay Melat Solomon Food insecurity and the risk of depression in people living with HIV/AIDS: a systematic review and meta-analysis AIDS Research and Therapy Food insecurity Depression HIV AIDS Systematic review Meta-analysis |
author_facet |
Getinet Ayano Light Tsegay Melat Solomon |
author_sort |
Getinet Ayano |
title |
Food insecurity and the risk of depression in people living with HIV/AIDS: a systematic review and meta-analysis |
title_short |
Food insecurity and the risk of depression in people living with HIV/AIDS: a systematic review and meta-analysis |
title_full |
Food insecurity and the risk of depression in people living with HIV/AIDS: a systematic review and meta-analysis |
title_fullStr |
Food insecurity and the risk of depression in people living with HIV/AIDS: a systematic review and meta-analysis |
title_full_unstemmed |
Food insecurity and the risk of depression in people living with HIV/AIDS: a systematic review and meta-analysis |
title_sort |
food insecurity and the risk of depression in people living with hiv/aids: a systematic review and meta-analysis |
publisher |
BMC |
series |
AIDS Research and Therapy |
issn |
1742-6405 |
publishDate |
2020-06-01 |
description |
Abstract Background The link between food insecurity and depression in people living with HIV/AIDS (PLWHA) has been explored in numerous studies; however, the existing evidence is inconclusive due to inconsistent results. Therefore, the objective of this systematic review and meta-analysis is to examine the relationship between food insecurity and depression in PLWHA. Methods We systematically searched PubMed, EMBASE, and Scopus to identify relevant studies. A random-effect model was used for conducting the meta-analysis. We assessed the risk of publication bias by funnel plot and Egger’s regression asymmetry test. Results In this review, seven studies were included in the final analysis. Our meta-analysis revealed that food insecurity significantly increased the risk of depression in PLWHA [RR 2.28 (95% CI 1.56–3.32)]. This association remained significant after adjusting for the confounding effects of drug use [RR 1.63 (95% CI 1.27–2.10)], social support [RR 2.21 (95% CI 1.18–4.16)] as well as ART drugs [RR 1.96 (95% CI 1.17–3.28)]. Our subgroup and sensitivity confirmed the robustness of the main analysis. Conclusion This systematic review and meta-analysis suggest a significant association between food insecurity and increased risk of depression PLWHA. Therefore, early screening and management of food insecurity in PLWHA seem to be necessary. |
topic |
Food insecurity Depression HIV AIDS Systematic review Meta-analysis |
url |
http://link.springer.com/article/10.1186/s12981-020-00291-2 |
work_keys_str_mv |
AT getinetayano foodinsecurityandtheriskofdepressioninpeoplelivingwithhivaidsasystematicreviewandmetaanalysis AT lighttsegay foodinsecurityandtheriskofdepressioninpeoplelivingwithhivaidsasystematicreviewandmetaanalysis AT melatsolomon foodinsecurityandtheriskofdepressioninpeoplelivingwithhivaidsasystematicreviewandmetaanalysis |
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1724621905974001664 |