Nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts enabled by NN2 pincer ligand

Nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts enabled by NN2 pincer ligand

Alkynes are amongst the most valuable functional groups in organic chemistry, however, the preparation of alkyl-substituted alkynes still remains elusive. Here the authors show a nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts.

Bibliographic Details
Main Authors: Xingjie Zhang, Di Qi, Chenchen Jiao, Xiaopan Liu, Guisheng Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25222-1
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spelling doaj-e7a2d5a6151041a5a7e81494eb88684a2021-08-15T11:40:29ZengNature Publishing GroupNature Communications2041-17232021-08-011211910.1038/s41467-021-25222-1Nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts enabled by NN2 pincer ligandXingjie Zhang0Di Qi1Chenchen Jiao2Xiaopan Liu3Guisheng Zhang4Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Henan Key Laboratory of Organic Functional Molecules and Drug Innovation, School of Chemistry and Chemical Engineering, Henan Normal UniversityKey Laboratory of Green Chemical Media and Reactions, Ministry of Education, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Henan Key Laboratory of Organic Functional Molecules and Drug Innovation, School of Chemistry and Chemical Engineering, Henan Normal UniversityKey Laboratory of Green Chemical Media and Reactions, Ministry of Education, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Henan Key Laboratory of Organic Functional Molecules and Drug Innovation, School of Chemistry and Chemical Engineering, Henan Normal UniversityKey Laboratory of Green Chemical Media and Reactions, Ministry of Education, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Henan Key Laboratory of Organic Functional Molecules and Drug Innovation, School of Chemistry and Chemical Engineering, Henan Normal UniversityKey Laboratory of Green Chemical Media and Reactions, Ministry of Education, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Henan Key Laboratory of Organic Functional Molecules and Drug Innovation, School of Chemistry and Chemical Engineering, Henan Normal UniversityAlkynes are amongst the most valuable functional groups in organic chemistry, however, the preparation of alkyl-substituted alkynes still remains elusive. Here the authors show a nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts.https://doi.org/10.1038/s41467-021-25222-1
collection DOAJ
language English
format Article
sources DOAJ
author Xingjie Zhang
Di Qi
Chenchen Jiao
Xiaopan Liu
Guisheng Zhang
spellingShingle Xingjie Zhang
Di Qi
Chenchen Jiao
Xiaopan Liu
Guisheng Zhang
Nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts enabled by NN2 pincer ligand
Nature Communications
author_facet Xingjie Zhang
Di Qi
Chenchen Jiao
Xiaopan Liu
Guisheng Zhang
author_sort Xingjie Zhang
title Nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts enabled by NN2 pincer ligand
title_short Nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts enabled by NN2 pincer ligand
title_full Nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts enabled by NN2 pincer ligand
title_fullStr Nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts enabled by NN2 pincer ligand
title_full_unstemmed Nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts enabled by NN2 pincer ligand
title_sort nickel-catalyzed deaminative sonogashira coupling of alkylpyridinium salts enabled by nn2 pincer ligand
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-08-01
description Alkynes are amongst the most valuable functional groups in organic chemistry, however, the preparation of alkyl-substituted alkynes still remains elusive. Here the authors show a nickel-catalyzed deaminative Sonogashira coupling of alkylpyridinium salts.
url https://doi.org/10.1038/s41467-021-25222-1
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AT diqi nickelcatalyzeddeaminativesonogashiracouplingofalkylpyridiniumsaltsenabledbynn2pincerligand
AT chenchenjiao nickelcatalyzeddeaminativesonogashiracouplingofalkylpyridiniumsaltsenabledbynn2pincerligand
AT xiaopanliu nickelcatalyzeddeaminativesonogashiracouplingofalkylpyridiniumsaltsenabledbynn2pincerligand
AT guishengzhang nickelcatalyzeddeaminativesonogashiracouplingofalkylpyridiniumsaltsenabledbynn2pincerligand
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