Sequential Treatment With Targeted and Immune Checkpoint Therapy in Patients With BRAF Positive Metastatic Melanoma: The Importance of Timing?

Sequential Treatment With Targeted and Immune Checkpoint Therapy in Patients With BRAF Positive Metastatic Melanoma: The Importance of Timing?

Background: Immune checkpoint- and targeted therapy have dramatically improved the therapeutic landscape in the management of BRAF mutation positive metastatic melanoma. However, pending the results of clinical trials, not only is it currently unclear whether immune checkpoint- or targeted therapy s...

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Bibliographic Details
Main Authors: Victoria Grätz, Detlef Zillikens, Hauke Busch, Ewan A. Langan, Patrick Terheyden
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Medicine
Subjects:
melanoma
sequential treatment
targeted therapy
immunotherapy
BRAF mutation
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2019.00257/full

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