Paraneoplastic bullous pemphigoid – A sign of clear cell renal carcinoma

Paraneoplastic bullous pemphigoid is a rare paraneoplastic syndrome. Rash is pruritic, with erythematous eruption of large subepidermal bullae over skin and often mucosal surfaces. We present an 84y woman with a three week history of erythematous rash, and 48hrs of bullae. A left clear cell renal ce...

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Bibliographic Details
Main Authors: Stuart R. Jackson, Jakob Koestenbauer, Adam P. Carroll, Than-Htike Oo, Shaun Chou, Balasubramaniam Indrajit
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Urology Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2214442020300073
Description
Summary:Paraneoplastic bullous pemphigoid is a rare paraneoplastic syndrome. Rash is pruritic, with erythematous eruption of large subepidermal bullae over skin and often mucosal surfaces. We present an 84y woman with a three week history of erythematous rash, and 48hrs of bullae. A left clear cell renal cell carcinoma was identified on CT imaging during the presentation. Subsequent removal of the tumour resulted in resolution of bullous pemphigoid symptoms. This first-of-kind case and successful result strengthens the association between renal cell carcinoma and paraneoplastic bullous pemphigoid, arguing for a high degree of clinical suspicion in unexplained presentations of bullous pemphigoid.
ISSN:2214-4420