Genetic causes of human NK cell deficiency and their effect on NK cell subsets

Human NK cells play critical roles in human host defense, particularly the control of viral infection and malignancy, and patients with congenital immunodeficiency affecting NK cell function or number can suffer from severe illness. The importance of NK cell function is particularly underscored in p...

Full description

Bibliographic Details
Main Authors: Emily M. Mace, Jordan S. Orange
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00545/full