miR-142-5p promotes cervical cancer progression by targeting LMX1A through Wnt/β-catenin pathway

Previous work has shown that miR-142-5p in cervical cancer tissues increased significantly compared with adjacent normal tissues. However, the function and the mechanism of miR-142-5p in cervical cancer have not been reported.

Bibliographic Details
Main Authors: Ke Lijuan, Chen Yanping, Li Yiying, Chen Zheng, He Yihui, Liu Jiahua, Zhuang Yingfeng
Format: Article
Language:English
Published: De Gruyter 2021-01-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2021-0218
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spelling doaj-e7dfa6979b1c47dea96707298cdbe3e42021-10-03T07:42:36ZengDe GruyterOpen Medicine2391-54632021-01-0116122423610.1515/med-2021-0218miR-142-5p promotes cervical cancer progression by targeting LMX1A through Wnt/β-catenin pathwayKe Lijuan0Chen Yanping1Li Yiying2Chen Zheng3He Yihui4Liu Jiahua5Zhuang Yingfeng6Department of Gynecology, Shengli Clinical Medical College of Fujian Medical University and Fujian Provincial Hospital, No. 134 Dong Street, Fuzhou, Fujian 350001, People’s Republic of ChinaDepartment of Gynecology, Shengli Clinical Medical College of Fujian Medical University and Fujian Provincial Hospital, No. 134 Dong Street, Fuzhou, Fujian 350001, People’s Republic of ChinaDepartment of Gynecology and Obstetrics, Shengli Clinical Medical College of Fujian Medical University and Fujian Provincial Hospital South Branch, No. 516 Jinrong South Street, Fuzhou, Fujian 350028, People’s Republic of ChinaDepartment of Gynecology, Shengli Clinical Medical College of Fujian Medical University and Fujian Provincial Hospital, No. 134 Dong Street, Fuzhou, Fujian 350001, People’s Republic of ChinaDepartment of Pathology, Shengli Clinical Medical College of Fujian Medical University and Fujian Provincial Hospital, No. 134 Dong Street, Fuzhou, Fujian 350001, People’s Republic of ChinaDepartment of Gynecology, Shengli Clinical Medical College of Fujian Medical University and Fujian Provincial Hospital, No. 134 Dong Street, Fuzhou, Fujian 350001, People’s Republic of ChinaDepartment of Critical Care Medicine, Shengli Clinical Medical College of Fujian Medical University and Fujian Provincial Hospital South Branch, No. 516 Jinrong South Street, Fuzhou, Fujian 350028, People’s Republic of ChinaPrevious work has shown that miR-142-5p in cervical cancer tissues increased significantly compared with adjacent normal tissues. However, the function and the mechanism of miR-142-5p in cervical cancer have not been reported.https://doi.org/10.1515/med-2021-0218mir-142-5pcervical cancerlmx1ahela cellswnt/β-catenin pathway
collection DOAJ
language English
format Article
sources DOAJ
author Ke Lijuan
Chen Yanping
Li Yiying
Chen Zheng
He Yihui
Liu Jiahua
Zhuang Yingfeng
spellingShingle Ke Lijuan
Chen Yanping
Li Yiying
Chen Zheng
He Yihui
Liu Jiahua
Zhuang Yingfeng
miR-142-5p promotes cervical cancer progression by targeting LMX1A through Wnt/β-catenin pathway
Open Medicine
mir-142-5p
cervical cancer
lmx1a
hela cells
wnt/β-catenin pathway
author_facet Ke Lijuan
Chen Yanping
Li Yiying
Chen Zheng
He Yihui
Liu Jiahua
Zhuang Yingfeng
author_sort Ke Lijuan
title miR-142-5p promotes cervical cancer progression by targeting LMX1A through Wnt/β-catenin pathway
title_short miR-142-5p promotes cervical cancer progression by targeting LMX1A through Wnt/β-catenin pathway
title_full miR-142-5p promotes cervical cancer progression by targeting LMX1A through Wnt/β-catenin pathway
title_fullStr miR-142-5p promotes cervical cancer progression by targeting LMX1A through Wnt/β-catenin pathway
title_full_unstemmed miR-142-5p promotes cervical cancer progression by targeting LMX1A through Wnt/β-catenin pathway
title_sort mir-142-5p promotes cervical cancer progression by targeting lmx1a through wnt/β-catenin pathway
publisher De Gruyter
series Open Medicine
issn 2391-5463
publishDate 2021-01-01
description Previous work has shown that miR-142-5p in cervical cancer tissues increased significantly compared with adjacent normal tissues. However, the function and the mechanism of miR-142-5p in cervical cancer have not been reported.
topic mir-142-5p
cervical cancer
lmx1a
hela cells
wnt/β-catenin pathway
url https://doi.org/10.1515/med-2021-0218
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