Effect of hyperbaric oxygen combined with drug therapy on cerebral blood flow characteristics, nerve injury and nerve cytokines in the convalescence of hypertensive cerebral hemorrhage
Objective: To study the effect of hyperbaric oxygen combined with drug therapy on cerebral blood flow characteristics, nerve injury and nerve cytokines in the convalescence of hypertensive cerebral hemorrhage. Methods: A total of 215 patients who were in convalescence of hypertension cerebral hem...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Editorial Board of Journal of Hainan Medical University
2017-07-01
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| Series: | Journal of Hainan Medical University |
| Subjects: | |
| Online Access: | http://www.hnykdxxb.com/PDF/201714/31.pdf |
| Summary: | Objective: To study the effect of hyperbaric oxygen combined with drug therapy on
cerebral blood flow characteristics, nerve injury and nerve cytokines in the convalescence
of hypertensive cerebral hemorrhage. Methods: A total of 215 patients who were in
convalescence of hypertension cerebral hemorrhage and treated in our hospital between
January 2013 and January 2017 were collected and divided into the control group (n=109)
who received conventional therapy and the observation group (n=106) who received adjuvant
hyperbaric oxygen therapy, and both therapies lasted for 1 month. The differences in nerve
function and neurotrophic state were compared between the two groups of patients before and
after treatment. Results: Before treatment, differences in the levels of cerebral hemodynamic
index levels as well as nerve injury index, amino acid neurotransmitter and neurotrophic
factor contents were not statistically significant between the two groups of patients. After 1
month of treatment, Vmean and Qmean levels as well as serum GABA, Gly, BDNF, NGF
and NTF contents of both groups of patients were higher than those before treatment while R
and Wv levels as well as serum S100B, GEAP, NSE, Glu and Asp contents were lower than
those before treatment, and Vmean and Qmean levels as well as serum GABA, Gly, BDNF,
NGF and NTF contents of observation group were higher than those of control group while
R and Wv levels as well as serum S100B, GEAP, NSE, Glu and Asp contents were lower
than those of control group. Conclusion: Adjuvant hyperbaric oxygen therapy can effectively
reduce the nerve injury and optimize |
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| ISSN: | 1007-1237 1007-1237 |