Statistical distance as a measure of physiological dysregulation is largely robust to variation in its biomarker composition.
Physiological dysregulation may underlie aging and many chronic diseases, but is challenging to quantify because of the complexity of the underlying systems. Recently, we described a measure of physiological dysregulation, DM, that uses statistical distance to assess the degree to which an individua...
Main Authors: | Alan A Cohen, Qing Li, Emmanuel Milot, Maxime Leroux, Samuel Faucher, Vincent Morissette-Thomas, Véronique Legault, Linda P Fried, Luigi Ferrucci |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4395377?pdf=render |
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