Tailoring Corynebacterium glutamicum towards increased malonyl-CoA availability for efficient synthesis of the plant pentaketide noreugenin
Abstract Background In the last years, different biotechnologically relevant microorganisms have been engineered for the synthesis of plant polyphenols such as flavonoids and stilbenes. However, low intracellular availability of malonyl-CoA as essential precursor for most plant polyphenols of intere...
Main Authors: | Lars Milke, Nicolai Kallscheuer, Jannick Kappelmann, Jan Marienhagen |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-04-01
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Series: | Microbial Cell Factories |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12934-019-1117-x |
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