Effect of soluble ICAM-1 on a Sjögren's syndrome-like phenotype in NOD mice is disease stage dependent.
Intercellular adhesion molecule-1 (ICAM-1) is involved in migration and co-stimulation of T and B cells. Membrane bound ICAM-1 is over expressed in the salivary glands (SG) of Sjögren's syndrome (SS) patients and has therefore been proposed as a potential therapeutic target. To test the utility...
Main Authors: | Nienke Roescher, Jelle L Vosters, Hongen Yin, Gabor G Illei, Paul P Tak, John A Chiorini |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-05-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3093404?pdf=render |
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