Exploring inhibitory mechanism of gallocatechin gallate on a-amylase and a-glucosidase relevant to postprandial hyperglycemia

Exploring inhibitory mechanism of gallocatechin gallate on a-amylase and a-glucosidase relevant to postprandial hyperglycemia

The postprandial hyperglycemia of diabetic patients is associated with a-amylase and a-glucosidase, searching safer enzyme inhibitors and deciphering their inhibition mechanism are important. In this study, gallocatechin gallate (GCG) was found to exert strong inhibition on α-amylase and α-glucosida...

Full description

Bibliographic Details
Main Authors:	Xiaqing Wu, Huafang Ding, Xing Hu, Junhui Pan, Yijing Liao, Deming Gong, Guowen Zhang
Format:	Article
Language:	English
Published:	Elsevier 2018-09-01
Series:	Journal of Functional Foods
Subjects:	Gallocatechin gallate α-Amylase α-Glucosidase Inhibitory mechanism
Online Access:	http://www.sciencedirect.com/science/article/pii/S175646461830358X

Similar Items

Pharmacokinetic study of gallocatechin-7-gallate from Pithecellobium clypearia Benth. in rats
by: Chao Li, et al.
Published: (2016-01-01)

Neuroprotective Effect of Gallocatechin Gallate on Glutamate-Induced Oxidative Stress in Hippocampal HT22 Cells
by: Do Hwi Park, et al.
Published: (2021-03-01)

A phlorotannin constituent of Ecklonia cava alleviates postprandial hyperglycemia in diabetic mice
by: Hyun-Ah Lee, et al.
Published: (2017-01-01)

Spiroindolone Analogues as Potential Hypoglycemic with Dual Inhibitory Activity on α-Amylase and α-Glucosidase
by: Mezna Saleh Altowyan, et al.
Published: (2019-06-01)

Chemical compositions, A-glucosidase and A-amylase inhibitory activities of crude polysaccharides from the endodermis of shaddock (Citrus maxima)
by: Liu Guocong
Published: (2012-01-01)

Gallocatechin gallate (GCG) inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation through MAPK and NF-κB signaling
by: Kai Kai Li, et al.
Published: (2017-03-01)

Hypoglycemic Efficacy of Docking Selected Natural Compounds against α-Glucosidase and α-Amylase
by: Jirawat Riyaphan, et al.
Published: (2018-09-01)

Effects of (−)-Gallocatechin-3-Gallate on Tetrodotoxin-Resistant Voltage-Gated Sodium Channels in Rat Dorsal Root Ganglion Neurons
by: Jian-Min Jiang, et al.
Published: (2013-05-01)

Synthesis and inhibitory activity of N-acetylpyrrolidine derivatives on α-glucosidase and α-amylase
by: Sompong Sansenya, et al.
Published: (2020-01-01)

Investigation of α-Amylase and α-Glucosidases Inhibitory Effects of Silybum marianum (L. Gaertn) Seed Extracts In Vitro
by: H Fallah Huseini, et al.
Published: (2012-02-01)

α-Amylase and α-Glucosidase Inhibition by Brown Seaweed (Sargassum sp) Extracts
by: Muhammad Firdaus, et al.
Published: (2014-12-01)

Inhibitory potential of Gossypium arboreum leaf extracts on diabetes key enzymes, α-amylase and α-glucosidase
by: Mutiu Idowu Kazeem, et al.
Published: (2013-04-01)

Alpha amylase and Alpha glucosidase inhibitory effects of aqueous stem extract of Salacia oblonga and its GC-MS analysis
by: Gladis Raja Malar Chelladurai, et al.
Published: (2018-05-01)

Momilactones A and B Are α-Amylase and α-Glucosidase Inhibitors
by: Nguyen Van Quan, et al.
Published: (2019-01-01)

α-Glucosidase and α-amylase inhibitory constituent of Carex baccans: Bio-assay guided isolation and quantification by validated RP-HPLC–DAD
by: Deepak Kumar, et al.
Published: (2013-01-01)

Five New Pregnane Glycosides from <i>Gymnema sylvestre</i> and Their α-Glucosidase and α-Amylase Inhibitory Activities
by: Phan Van Kiem, et al.
Published: (2020-05-01)

Possible anti-diabetic potentials of Annona muricata (soursop): inhibition of α-amylase and α-glucosidase activities
by: Kinsgley Chukwunonso Agu, et al.
Published: (2019-06-01)

Development of an antidiabetic formulation (ADJ6) and its inhibitory activity against α-amylase and α-glucosidase
by: Anand Duraiswamy, et al.
Published: (2016-07-01)

Isolated compounds from Dracaena angustifolia Roxb and acarbose synergistically/additively inhibit α-glucosidase and α-amylase: an in vitro study
by: Chen, G., et al.
Published: (2022)

α-Amylase and α-glucosidase inhibitory activities of the extracts and constituents of Ferulago blancheana, F. pachyloba and F. trachycarpa roots
by: Songül Karakaya, et al.
Published: (2018-02-01)

In Vitro Inhibition of α-Amylase and α-Glucosidase by Different Parts of Amla Plant (Phyllanthus emblica L)
by: Novi I. Fauzi, et al.
Published: (2018-12-01)

Heat stability of the in vitro inhibitory effect of spices on lipase, amylase, and glucosidase enzymes
by: Irushika T. Fernando, et al.
Published: (2019-02-01)

Two Extracts From Manihot Esculenta Leaves Efficiently Inhibit α-Glucosidase and α-Amylase: A New Approach for the Management of Diabetes
by: Israel Oghenevwodokohwo Okoro
Published: (2020-07-01)

Effect of Polar and Nom-polar Aloe vera L. Leaf Extracts on α-amylase and α-Glucosidases Inhibitory Activity In vitro
by: H Fallah Huseini, et al.
Published: (2013-12-01)

Comprehensive enzymatic analysis of the amylolytic system in the digestive fluid of the sea hare, Aplysia kurodai: Unique properties of two α-amylases and two α-glucosidases
by: Akihiko Tsuji, et al.
Published: (2014-01-01)

Effect of storage time on antioxidant activity and inhibition on α‐Amylase and α‐Glucosidase of white tea
by: Ping Xu, et al.
Published: (2019-02-01)

Inhibitory Effects of Solvent-Partitioned Fractions of Two Nigerian Herbs (Spondias mombin Linn. and Mangifera indica L.) on α-Amylase and α-Glucosidase
by: Oluwafemi Adeleke Ojo, et al.
Published: (2018-05-01)

Inhibitory effects of Ligustrum robustum (Rxob.) Blume extract on α-amylase and α-glucosidase
by: Zhi-Long Yu, et al.
Published: (2015-12-01)

Aspulvinones Suppress Postprandial Hyperglycemia as Potent α-Glucosidase Inhibitors From Aspergillus terreus ASM-1
by: Changjing Wu, et al.
Published: (2021-08-01)

Screening natural product extracts for potential enzyme inhibitors: protocols, and the standardisation of the usage of blanks in α-amylase, α-glucosidase and lipase assays
by: Chintha Lankatillake, et al.
Published: (2021-01-01)

Ephedra alata fruit extracts: phytochemical screening, anti-proliferative activity and inhibition of DPPH, α-amylase, α-glucosidase, and lipase enzymes
by: Nidal Jaradat, et al.
Published: (2021-06-01)

Drying alters the phenolic constituents, antioxidant properties, α‐amylase, and α‐glucosidase inhibitory properties of Moringa (Moringa oleifera) leaf
by: Adedayo O. Ademiluyi, et al.
Published: (2018-11-01)

Structural Dependence of Sulfated Polysaccharide for Diabetes Management: Fucoidan From Undaria pinnatifida Inhibiting α-Glucosidase More Strongly Than α-Amylase and Amyloglucosidase
by: Hui Si Audrey Koh, et al.
Published: (2020-06-01)

In-Vitro α-amylase, α-glucosidase Inhibitory Activities and In-Vivo Anti-Hyperglycemic Potential of Different Dosage Forms of Guduchi (Tinospora Cordifolia [Willd.] Miers) Prepared With Ayurvedic Bhavana Process
by: Rohit Sharma, et al.
Published: (2021-05-01)

Phytochemical Properties and Inhibitory and Antioxidant Effects of the Decoction, Infusion and Hydro-Alcoholic Extract of Nepeta Race-mosa on α-Amylase and α-Glucosidase
by: MohammadMehdi Zarrabi, et al.
Published: (2019-06-01)

Total flavonoid contents and in silico study of flavonoid compounds from Meniran (Phyllanthus niruri L.) towards alpha-amylase and alpha-glucosidase enzyme
by: Sri Luliana, et al.
Published: (2019-05-01)

Washingtonia filifera seed extracts inhibit the islet amyloid polypeptide fibrils formations and α-amylase and α-glucosidase activity
by: Sonia Floris, et al.
Published: (2021-01-01)

Identification of bioactive compounds by GC-MS and α-amylase and α-glucosidase inhibitory activity of Rauvolfia tetraphylla L. and Oroxylum indicum (L.) Kurz: an in vitro and in silico approach
by: Ananta Swargiary, et al.
Published: (2020-11-01)

Metabolite profiling and inhibitory properties of leaf extracts of Ficus benjamina towards α-glucosidase and α-amylase
by: Muhammad Waseem Mumtaz, et al.
Published: (2018-01-01)

Synthesis of novel indole, 1,2,4-triazole derivatives as potential glucosidase inhibitors
by: Ramesh S Gani, et al.
Published: (2020-12-01)